Evidence map›Paper›PMID 34417331›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Visual Cortical Area MT Is Required for Development of the Dorsal Stream and Associated Visuomotor Behaviors.

William C Kwan, Chia-Kang Chang, Hsin-Hao Yu, Inaki C Mundinano, Dylan M Fox, Jihane Homman-Ludiye, James A Bourne

Open access · hybridAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  4. Development of Higher-Level Vision: A Network Perspective.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

William C KwanAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria 3800, Australia.
Chia-Kang ChangAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria 3800, Australia.
Hsin-Hao YuDepartment of Physiology, Monash University, Clayton, Victoria 3800, Australia.ORCID 0000-0003-3704-2258
Inaki C MundinanoAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria 3800, Australia.
Dylan M FoxAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria 3800, Australia.
Jihane Homman-LudiyeAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria 3800, Australia.
James A BourneAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria 3800, Australia James.Bourne@monash.edu.ORCID 0000-0002-0902-3108
Australian Regenerative Medicine Institute · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The middle temporal (MT) area of the extrastriate visual cortex has long been studied in adulthood for its distinctive physiological properties and function as a part of the dorsal stream, yet interestingly it possesses a similar maturation profile as the primary visual cortex (V1). Here, we examined whether an early-life lesion in MT of marmoset monkeys (six female, two male) altered the dorsal stream development and the behavioral precision of reaching-to-grasp sequences. We observed permanent changes in the anatomy of cortices associated with both reaching (parietal and medial intraparietal areas) and grasping (anterior intraparietal area), as well as in reaching-and-grasping behaviors. In addition, we observed a significant impact on the anatomy of V1 and the direction sensitivity of V1 neurons in the lesion projection zone. These findings indicate that area MT is a crucial node in the development of primate vision, affecting both V1 and areas in the dorsal visual pathway known to mediate visually guided manual behaviors.

Indexed as

AnimalsCallithrixFemaleMaleMotion PerceptionNeuronsPhotic StimulationPsychomotor PerformanceVisual CortexVisual PathwaysVisual Perceptionlesionmarmosetmiddle temporal areaMRIvisual cortex

Identifiers

PMID34417331
PMCPMC8482858
OpenAlexW3193628157

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.