Evidence map›Paper›PMID 34417297›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Cryo-EM structures of

Jiao Li, Long Han, Francesca Vallese, Ziqiao Ding, Sylvia K Choi, Sangjin Hong, Yanmei Luo, Bin Liu, Chun Kit Chan, Emad Tajkhorshid and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 37 citations in OpenAlex.

  1. Distinct ubiquinone binding at the oxidation and reduction sites of cytochrome bcProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Effect of Ammonia onAntioxidants (Basel, Switzerland) · 2026
    Article
  3. The Evolution of Lipids from Solvents to Substrates.Annual review of biophysics · 2026
    Review
  4. Article
  5. Structure of Acinetobacter baumannii cytochrome boThe Journal of biological chemistry · 2026
    Article
  6. Article
  7. Evidence for ethanol-dependent acetic acid resistance inApplied and environmental microbiology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Carbon Monoxide and Prokaryotic Energy Metabolism.International journal of molecular sciences · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Membrane-Bound Redox Enzyme CytochromeInternational journal of molecular sciences · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Jiao LiSchool of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Long HanDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.
Francesca ValleseDepartment of Anesthesiology, Columbia University, New York, NY 10032.
Ziqiao DingDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0002-0824-4734
Sylvia K ChoiDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0003-3330-8012
Sangjin HongDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Yanmei LuoSchool of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Bin LiuSchool of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Chun Kit ChanDepartment of Physics, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Emad TajkhorshidDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.ORCID 0000-0001-8434-1010
Jiapeng ZhuSchool of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China; r-gennis@illinois.edu jack.zhang@yale.edu oc2188@cumc.columbia.edu zhujiapeng@hotmail.com.ORCID 0000-0002-9165-0126
Oliver ClarkeDepartment of Anesthesiology, Columbia University, New York, NY 10032; r-gennis@illinois.edu jack.zhang@yale.edu oc2188@cumc.columbia.edu zhujiapeng@hotmail.com.ORCID 0000-0003-1876-196X
Kai ZhangDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511; r-gennis@illinois.edu jack.zhang@yale.edu oc2188@cumc.columbia.edu zhujiapeng@hotmail.com.
Robert GennisDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801; r-gennis@illinois.edu jack.zhang@yale.edu oc2188@cumc.columbia.edu zhujiapeng@hotmail.com.ORCID 0000-0002-3805-6945
University of Illinois Urbana-Champaign · USNanjing University of Chinese Medicine · CNColumbia University · USYale University · US

Funding

WHOLE CELL SIMULATIONP41GM104601 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI TAJKHORSHID, EMAD · 2012 to 2021
$19.0M
NIGMS NIH HHS P41 GM104601
6 · The paper itself

Abstract

Two independent structures of the proton-pumping, respiratory cytochrome

Indexed as

Proton PumpsBinding SitesCryoelectron MicroscopyCytochrome b GroupEscherichia coliEscherichia coli ProteinsHemeOxidation-ReductionPhospholipidsProtein ConformationUbiquinoneCytochrome b Groupcytochrome bo3, E coliEscherichia coli ProteinsHemePhospholipidsProton PumpsUbiquinoneubiquinone 8bioenergeticselectron transportheme–copper oxidoreductaseproton pumpubiquinone

Identifiers

PMID34417297
PMCPMC8403832
OpenAlexW3195579945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.