Evidence map›Paper›PMID 34417282›Full record

ArticleeNeuro

Differential Retinoic Acid Signaling in the Hippocampus of Aged Rats with and without Memory Impairment.

Marta U Wołoszynowska-Fraser, Sharyn L Rossi, Jeffrey M Long, Peter J McCaffery, Peter R Rapp

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Marta U Wołoszynowska-FraserLaboratory of Behavioral Neuroscience, Neurocognitive Aging Section, National Institute on Aging, Baltimore, MD 21224.
Sharyn L RossiLaboratory of Behavioral Neuroscience, Neurocognitive Aging Section, National Institute on Aging, Baltimore, MD 21224.
Jeffrey M LongLaboratory of Behavioral Neuroscience, Neurocognitive Aging Section, National Institute on Aging, Baltimore, MD 21224.
Peter J McCafferyInstitute of Medical Science, School of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland, United Kingdom.
Peter R RappLaboratory of Behavioral Neuroscience, Neurocognitive Aging Section, National Institute on Aging, Baltimore, MD 21224 rappp@mail.nih.gov.ORCID 0000-0002-0983-3944
Institute on Aging · USUniversity of Aberdeen · GB

Funding

Neurocognitive Aging: Experience-Dependent Dynamics, Plasticity and Network ContributionsZIAAG000350 · NIA · NATIONAL INSTITUTE ON AGING · PI RAPP, PETER R · 2009 to 2025
$30.9M
Intramural NIH HHS ZIA AG000350
6 · The paper itself

Abstract

Retinoic acid (RA), a metabolite of vitamin A, has many physiological functions, and mounting evidence points to important roles in cognition.

Indexed as

HippocampusTretinoinAnimalsCognitionMaze LearningMemory DisordersRatsSpatial MemoryTretinoinaginghippocampusmemoryretinoic acidspatialvitamin A

Identifiers

PMID34417282
PMCPMC8442538
OpenAlexW3194151968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.