Evidence map›Paper›PMID 34417182›Full record

ArticleScience advances2021

Identification and assessment of cardiolipin interactions with

Robin A Corey, Wanling Song, Anna L Duncan, T Bertie Ansell, Mark S P Sansom, Phillip J Stansfeld

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
  2. Article
  3. Dark Side ofJournal of the American Chemical Society · 2026
    Article
  4. Article
  5. A surface-exposed cardiolipin synthase provides an unexpected paradigm for maintaining the Gram-negative outer membrane.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. A Minimalist Model Lipid System Mimicking the Biophysical Properties ofLangmuir : the ACS journal of surfaces and colloids · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. OXA β-lactamases frombioRxiv : the preprint server for biology · 2024
    Article
  16. Emerging Designs and Applications for Biomembrane Biosensors.Annual review of analytical chemistry (Palo Alto, Calif.) · 2024
    Review
  17. Structure and mechanism of the KNature communications · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Robin A CoreyDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.ORCID 0000-0003-1820-7993
Wanling SongDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Anna L DuncanDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.ORCID 0000-0001-9873-4552
T Bertie AnsellDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.ORCID 0000-0003-4870-5387
Mark S P SansomDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.ORCID 0000-0001-6360-7959
Phillip J StansfeldDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK. phillip.stansfeld@warwick.ac.uk.ORCID 0000-0001-8800-7669
University of Oxford · GBUniversity of Warwick · GB

Funding

Biotechnology and Biological Sciences Research Council BB/L01386X/1Biotechnology and Biological Sciences Research Council BB/R00126X/1Medical Research Council MR/S009213/1Wellcome Trust
6 · The paper itself

Abstract

Integral membrane proteins are localized and/or regulated by lipids present in the surrounding bilayer. While bacteria have relatively simple membranes, there is ample evidence that many bacterial proteins bind to specific lipids, especially the anionic lipid cardiolipin. Here, we apply molecular dynamics simulations to assess lipid binding to 42 different

Indexed as

CardiolipinsEscherichia coliBacterial ProteinsLipid BilayersMembrane ProteinsMolecular Dynamics SimulationBacterial ProteinsCardiolipinsLipid BilayersMembrane Proteins

Identifiers

PMID34417182
PMCPMC8378812
OpenAlexW3195672811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.