Evidence map›Paper›PMID 34417177›Full record

ArticleScience advances2021

Identification and architecture of a putative secretion tube across mycobacterial outer envelope.

Xiaoying Cai, Lei Liu, Chunhong Qiu, Chongzheng Wen, Yao He, Yanxiang Cui, Siyu Li, Xuan Zhang, Longhua Zhang, Changlin Tian and 3 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Impact of MSMEG5257 Deletion onMicroorganisms · 2024
    Article
  4. Article
  5. Yin and yang regulation of stress granules by Caprin-1.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Xiaoying CaiSchool of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China.ORCID 0000-0001-6694-2154
Lei LiuHefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, Anhui, China.ORCID 0000-0001-9544-5819
Chunhong QiuSchool of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China.ORCID 0000-0002-2647-7849
Chongzheng WenHefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, Anhui, China.ORCID 0000-0002-0099-7395
Yao HeCalifornia NanoSystems Institute, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.ORCID 0000-0002-1368-6422
Yanxiang CuiCalifornia NanoSystems Institute, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA.ORCID 0000-0002-8909-6576
Siyu LiSchool of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China.ORCID 0000-0001-6455-3956
Xuan ZhangInstitute of Health Science, Institutes of Physical Science and Information Technology, Anhui University, Hefei, Anhui, China.
Longhua ZhangSchool of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China.
Changlin TianSchool of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China.
Lijun BiInstitute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Z Hong ZhouCalifornia NanoSystems Institute, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA. wgong@ustc.edu.cn hong.zhou@ucla.edu.ORCID 0000-0002-8373-4717
Weimin GongSchool of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China. wgong@ustc.edu.cn hong.zhou@ucla.edu.ORCID 0000-0002-6723-1298
University of Science and Technology of China · CNCalifornia NanoSystems Institute · USAnhui University · CNChinese Academy of Sciences · CN

Funding

Genome Structure, Transcription and Packaging of dsRNA VirusesR01AI094386 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Z Hong ZHOU · 2012 to 2026
$6.0M
High-Resolution CryoEM Reconstruction of Large ComplexesR01GM071940 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHOU, Z HONG · 2006 to 2025
$5.0M
In situ atomic structures of the Kaposi's sarcoma-associated herpesvirus portal-terminase complex and glycoproteinsR01DE025567 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WU, TING-TING, ZHOU, Z HONG · 2016 to 2024
$4.0M
Structural basis of human cytomegalovirus replication within host cellsR01DE028583 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Z Hong ZHOU · 2019 to 2026
$3.2M
West/Midwest Consortium for High-Resolution Cryo Electron MicroscopyU24GM116792 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AGBANDJE-MCKENNA, MAVIS, DOKLAND, TERJE · 2016 to 2020
$3.0M
HIGH-END CRYOEM INSTRUMENT FOR UCLA ELECTRON IMAGING CTR FOR NANOMACHINES: AIDSS10RR023057 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2006 to 2006
$1.6M
NCRR NIH HHS S10 RR023057NIAID NIH HHS R01 AI094386NIDCR NIH HHS R01 DE025567NIDCR NIH HHS R01 DE028583NIGMS NIH HHS R01 GM071940NIGMS NIH HHS U24 GM116792
6 · The paper itself

Abstract

Tuberculosis-causing mycobacteria have thick cell-wall and capsule layers that are formed from complex structures. Protein secretion across these barriers depends on a specialized protein secretion system, but none has been reported. We show that

Indexed as

Bacterial ProteinsMycobacterium tuberculosisCell WallMycobacterium smegmatisBacterial Proteins

Identifiers

PMID34417177
PMCPMC8378821
OpenAlexW3194594029

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.