Evidence map›Paper›PMID 34416851›Full record

ArticleBMC infectious diseases2021

Comparative analysis of carbapenemases, RND family efflux pumps and biofilm formation potential among Acinetobacter baumannii strains with different carbapenem susceptibility.

Yanpeng Zhang, Bing Fan, Yong Luo, Zhiyuan Tao, Yongbo Nie, Yongtao Wang, Fanglin Ding, Yanwu Li, Dayong Gu

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Clonal lineage and biofilm growth shape cefiderocol activity inFrontiers in cellular and infection microbiology · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Molecular and clinical epidemiology of carbapenem resistantThe Lancet regional health. Western Pacific · 2024
    Article
  7. Article
  8. Microorganisms · 2023
    Article
  9. Synergistic Role of Biofilm-Associated Genes and Efflux Pump Genes in Tigecycline Resistance of Acinetobacter baumannii.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  10. Review
  11. Efflux-Related Carbapenem Resistance inInternational journal of molecular sciences · 2023
    Article
  12. Drug‑resistantExperimental and therapeutic medicine · 2023
    Review
  13. Review
  14. Article
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yanpeng Zhang *Department of Clinical Laboratory, Shenzhen Institute of Translational Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, No. 3002, Sungang Xi Road, Shenzhen, 518035, China. 61468307@qq.com.
Bing Fan *Department of Clinical Laboratory, Shenzhen Institute of Translational Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, No. 3002, Sungang Xi Road, Shenzhen, 518035, China.
Yong LuoDepartment of Clinical Laboratory, Shenzhen Institute of Translational Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, No. 3002, Sungang Xi Road, Shenzhen, 518035, China.
Zhiyuan TaoDepartment of Clinical Laboratory, Shenzhen Institute of Translational Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, No. 3002, Sungang Xi Road, Shenzhen, 518035, China.
Yongbo NieDepartment of Clinical Laboratory, Shenzhen Institute of Translational Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, No. 3002, Sungang Xi Road, Shenzhen, 518035, China.
Yongtao WangDepartment of Clinical Laboratory, Wuhan No.1 Hospital, Zhongshan Road, Wuhan, China.
Fanglin DingDepartment of Clinical Laboratory, Shenzhen Institute of Translational Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, No. 3002, Sungang Xi Road, Shenzhen, 518035, China.
Yanwu LiDepartment of Clinical Laboratory, Shenzhen Institute of Translational Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, No. 3002, Sungang Xi Road, Shenzhen, 518035, China. 13554769888@163.com.
Dayong GuDepartment of Clinical Laboratory, Shenzhen Institute of Translational Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, No. 3002, Sungang Xi Road, Shenzhen, 518035, China. wanhood@163.com.
Shenzhen Second People's Hospital · CNWuhan No.1 Hospital · CN

Funding

Basic research project of Shenzhen Science and technology innovation Commission No. JCYJ20190806164011195
6 · The paper itself

Abstract

aimThis study has conducted a comparative analysis of common carbapenemases harboring, the expression of resistance-nodulation-cell division (RND) family efflux pumps, and biofilm formation potential associated with carbapenem resistance among Acinetobacter baumannii (A. baumannii) strains with different carbapenem susceptibility.

methodsA total of 90 isolates of A. baumannii from two tertiary hospitals of China were identified and grouped as carbapenem susceptible A. baumannii (CSAB) strains and carbapenem non-susceptible A. baumannii (CnSAB) strains based on the susceptibility to imipenem. Harboring of carbapenemase genes, relative expression of RND family efflux pumps and biofilm formation potential were compared between the two groups.

resultAmong these strains, 12 (13.3 %) strains were divided into the CSAB group, and 78 (86.7 %) strains into the CnSAB group. Compared with CSAB strains, CnSAB strains increased distribution of bla

conclusionsClinically, harboring more bla

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesBiofilmsCarbapenemsCell DivisionMicrobial Sensitivity TestsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemsAcinetobacter baumanniiBiofilmCarbapenemasesEfflux pumpResistance

Identifiers

PMID34416851
PMCPMC8377947
OpenAlexW3194249259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.