Evidence map›Paper›PMID 34415790›Full record

ArticleJCO clinical cancer informatics2021

Online Platform to Assess Complex Social Relationships and Patient-Reported Outcomes Among Adolescent and Young Adult Cancer Survivors.

Pragya G Poudel, Hailey E Bauer, D Kumar Srivastava, Kevin R Krull, Melissa M Hudson, Leslie L Robison, Zhaoming Wang, I-Chan Huang

Open access · greenAbstract read
In one paragraph

Article in JCO clinical cancer informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. The association among psychological factors, pain severity and quality of life in people living beyond adolescent and young adult cancer: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Pooled it
  2. Management of late toxicities and specific follow-up needs of adolescent and young adult cancer survivors: recommendations from scientific societies in Spain.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
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  12. Experiences of adolescent and young adult cancer survivors during the COVID-19 pandemic.Journal of cancer survivorship : research and practice · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Pragya G PoudelDepartment of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, TN.
Hailey E BauerDepartment of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-3459-9950
D Kumar SrivastavaDepartment of Biostatistics, St Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0001-6693-8120
Kevin R KrullDepartment of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-0476-7001
Melissa M HudsonDepartment of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0001-6984-2407
Leslie L RobisonDepartment of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0001-7460-8578
Zhaoming WangDepartment of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0001-7556-3869
I-Chan HuangDepartment of Epidemiology and Cancer Control, St Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0002-1194-3923
St. Jude Children's Research Hospital · US

Funding

Women's Cancer Research ProgramP30CA014236 · NCI · DUKE UNIVERSITY · PI JOHN N. NORTON · 1985 to 2026
$174.8M
Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Using Item Response Theory to Improve Children's Quality of Life AssessmentK23HD057146 · NICHD · UNIVERSITY OF FLORIDA · PI HUANG, I-CHAN · 2009 to 2011
$378k
NCI NIH HHS P30 CA014236NCI NIH HHS P30 CA021765NICHD NIH HHS K23 HD057146
6 · The paper itself

Abstract

purposeSocial integration and relationship issues have been understudied among adolescent and young adult (AYA) cancer survivors. This study compared social relationships (social networks, support, and isolation) between AYA cancer survivors and noncancer controls, and identified social integration mechanisms through which the cancer experience influences patient-reported outcomes (PROs). MATERIALS AND

methodsOne hundred two AYA cancer survivors and 102 age, sex, and race-matched noncancer controls from a national Internet panel completed an online survey to identify up to 25 of closest friends and relatives whom they have contacted within the past 2 years. Participants' interpersonal connections were used to create a social network index. The Duke-UNC Functional Social Support Questionnaire, UCLA Loneliness Scale, and PROMIS-29 Profile were used to measure social support, perceived isolation or loneliness, and PROs (physical functioning, pain interference, fatigue, anxiety, and depression domains), respectively. Path analysis tested effects of cancer experience on PROs using serial social relationship variables as mediators.

resultsCompared with controls, survivors of lymphoma, leukemia, and solid tumor had better social networks; however, survivors of solid tumor and central nervous system malignancies had higher perceived loneliness (all

conclusionCompared with controls, survivors were more socially connected but experienced greater loneliness, which was associated with poorer PROs. Screening social integration issues during follow-up care and providing appropriate interventions are warranted.

Indexed as

Cancer SurvivorsNeoplasmsAdolescentAnxietyHumansInterpersonal RelationsLonelinessPatient Reported Outcome MeasuresYoung Adult

Identifiers

PMID34415790
PMCPMC8812647
OpenAlexW3194080909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.