Evidence map›Paper›PMID 34415481›Full record

ReviewJournal of medical ultrasonics (2001)2021

Diagnostic accuracy of ultrasound-guided attenuation parameter as a noninvasive test for steatosis in non-alcoholic fatty liver disease.

Hidekatsu Kuroda, Tamami Abe, Yudai Fujiwara, Tomoaki Nagasawa, Yasuhiro Takikawa

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of medical ultrasonics (2001), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hidekatsu KurodaDivision of Hepatology, Department of Internal Medicine, Iwate Medical University, Nishitokuta 2-1-1, Yahaba-cho, Shiwa-gun, Iwate, 028-3694, Japan. hikuro@iwate-med.ac.jp.ORCID http://orcid.org/0000-0002-1471-1087
Tamami AbeDivision of Hepatology, Department of Internal Medicine, Iwate Medical University, Nishitokuta 2-1-1, Yahaba-cho, Shiwa-gun, Iwate, 028-3694, Japan.
Yudai FujiwaraDivision of Hepatology, Department of Internal Medicine, Iwate Medical University, Nishitokuta 2-1-1, Yahaba-cho, Shiwa-gun, Iwate, 028-3694, Japan.
Tomoaki NagasawaDivision of Hepatology, Department of Internal Medicine, Iwate Medical University, Nishitokuta 2-1-1, Yahaba-cho, Shiwa-gun, Iwate, 028-3694, Japan.
Yasuhiro TakikawaDivision of Hepatology, Department of Internal Medicine, Iwate Medical University, Nishitokuta 2-1-1, Yahaba-cho, Shiwa-gun, Iwate, 028-3694, Japan.
Iwate Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to evaluate the diagnostic accuracy of the ultrasound-guided attenuation parameter (UGAP) using the LOGEQ E10 for hepatic steatosis in non-alcoholic fatty liver disease (NAFLD) patients and directly compare UGAP with attenuation imaging (ATI) and controlled attenuation parameter (CAP). We prospectively analyzed 105 consecutive patients with NAFLD who underwent UGAP, ATI, CAP, and liver biopsy on the same day between October 2019 and April 2021. The diagnostic ability of the UGAP-determined attenuation coefficient (AC) was evaluated using receiver operating characteristic (ROC) curve analysis, and its correlation with ATI-determined AC values or CAP values was investigated. The success rate of UGAP was 100%. The median IQR/med obtained by UGAP was 4.0%, which was lower than that of ATI and CAP (P < 0.0001). The median ACs obtained by UGAP for grades S0 (control), S1, S2, and S3 were 0.590, 0.670, 0.750, and 0.845 dB/cm/MHz, respectively, demonstrating a stepwise increase with increasing hepatic steatosis severity (P < 0.0001). The areas under the ROC curve of UGAP for identifying ≥ S1, ≥ S2, and S3 were 0.890, 0.906, and 0.912, respectively, which were significantly better than the results obtained with CAP for identifying S3. Furthermore, the correlation coefficient between UGAP-AC and ATI-AC values was 0.803 (P < 0.0001), indicating a strong relationship. Our results indicate that UGAP has high diagnostic accuracy for detecting and grading hepatic steatosis in patients with NAFLD.

Indexed as

Elasticity Imaging TechniquesNon-alcoholic Fatty Liver DiseaseBiopsyHumansLiverPredictive Value of TestsROC CurveUltrasonography, InterventionalAttenuation coefficientHepatic steatosisNon-alcoholic fatty liver diseaseUltrasound-guided attenuation parameter

Identifiers

PMID34415481
OpenAlexW3195765745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.