Evidence map›Paper›PMID 34415466›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2022

Specificities of acute cholangitis in patients with cancer: a retrospective comparative study of 130 episodes.

Aurélien Sokal, Sylvain Chawki, Yann Nguyen, Alain Sauvanet, Philippe Ponsot, Frédérique Maire, Bruno Fantin, Victoire de Lastours

Abstract read
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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. ShortWorld journal of gastroenterology · 2023
    Pooled it
  2. Article
  3. Evaluation of factors associated with drug fever following gemcitabine and nanoparticle albumin-bound paclitaxel treatment for pancreatic cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Clinical and microbiological characteristics of reflux cholangitis following bilio-enteric anastomosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Aurélien SokalService de Médecine Interne, Hôpital Beaujon, Assistance-Publique Hôpitaux de Paris, 92100, Clichy, France.
Sylvain ChawkiService de Médecine Interne, Hôpital Beaujon, Assistance-Publique Hôpitaux de Paris, 92100, Clichy, France.
Yann NguyenService de Médecine Interne, Hôpital Beaujon, Assistance-Publique Hôpitaux de Paris, 92100, Clichy, France.
Alain SauvanetService de Chirurgie Hépatobiliaire, Hôpital Beaujon, Assistance-Publique Hôpitaux de Paris, 92100, Clichy, France.
Philippe PonsotService de Pancréatologie, Hôpital Beaujon, Assistance-Publique Hôpitaux de Paris, 92100, Clichy, France.
Frédérique MaireService de Pancréatologie, Hôpital Beaujon, Assistance-Publique Hôpitaux de Paris, 92100, Clichy, France.
Bruno FantinService de Médecine Interne, Hôpital Beaujon, Assistance-Publique Hôpitaux de Paris, 92100, Clichy, France.
Victoire de LastoursService de Médecine Interne, Hôpital Beaujon, Assistance-Publique Hôpitaux de Paris, 92100, Clichy, France. victoire.de-lastours@aphp.fr.ORCID http://orcid.org/0000-0003-1160-2069
Hôpital Beaujon · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic and biliary duct cancers are increasing causes of acute cholangitis (AC). We retrospectively characterize 81 cancer-associated cholangitis (CAC) compared to 49 non-cancer-associated cholangitis (NCAC). Clinical and biological presentations were similar. However, in CAC, antibiotic resistance and inadequate empirical antibiotic therapy were more frequent; more patients required ≥ 2 biliary drainages; and mortality at day 28 was higher than in NCAC. Death was associated with initial severity and CAC in a multivariate analysis. Cholangitis associated with pancreatic or biliary duct cancers requires specific empirical antimicrobial therapy; early use of biliary drainage may improve outcomes.

Indexed as

Acute DiseaseAgedAged, 80 and overAnti-Bacterial AgentsCholangitisFemaleHumansMaleMiddle AgedNeoplasmsRetrospective StudiesAnti-Bacterial AgentsAntibiotic resistanceBacterial cholangitisBiliary drainageCancer

Identifiers

PMID34415466
OpenAlexW3193507305

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.