ArticleActa neurochirurgica2022
Risk factors for intracranial aneurysm rupture in pediatric patients.
Article in Acta neurochirurgica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Ruptured intraventricular aneurysm in the setting of diffuse cerebral venous congenital abnormalities in a pediatric patient.Radiology case reports · 2026Article
- Individualized treatment for pediatric intracranial aneurysms in China: case series and literature review.Frontiers in surgery · 2026Article
- Infantile ruptured acom aneurysm treated with endovascular stent-coil embolization: case report.BMC neurology · 2025Article
- Ruptured distal middle cerebral artery aneurysm in a pediatric patient: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Pediatric anterior choroidal artery aneurysm successfully coiled after re-rupture.The neuroradiology journal · 2024Article
- Focal drug-resistant temporal lobe epilepsy associated with an ipsilateral anterior choroidal artery aneurysm: illustrative case.Journal of neurosurgery. Case lessons · 2023Article
- Tissue adhesive hemostatic microneedle arrays for rapid hemorrhage treatment.Bioactive materials · 2023Article
- Saccular intracranial neonatal aneurysm.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Review
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5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundIntracranial aneurysm (IA) rupture in pediatric patients is a rare but fatal condition. Although risk factors for aneurysm rupture in adults have been well documented, they remain unknown in pediatric patients.
methodsData for 94 pediatric patients with IAs were retrospectively analyzed. The patients were divided into ruptured and unruptured groups. Risk factors for aneurysm rupture were analyzed through univariable and multiple logistic regression analyses. Typical patients with risk factors were described.
resultsUnivariable analyses showed that the unruptured group had significantly higher percentages of giant aneurysms (43.2% vs 12.3%, P = 0.002), wide-neck aneurysms (67.6% vs 29.8%, P = 0.001), and aneurysms located in the internal carotid artery (40.5% vs 3.5%, P < 0.001), while the ruptured group had significantly higher percentages of patients younger than 5 years old (28.1% vs 5.4%, P = 0.013) and aneurysms located in the anterior cerebral artery (24.6% vs 5.4%, P = 0.032), posterior cerebral artery (14.0% vs 0%, P = 0.045), and distal arterial region (DAR) (46.8% vs 27.0%, P < 0.001). Multiple logistic regression analysis confirmed that age 0-5 years (OR = 6.844, P = 0.042) and IAs located in the DAR (OR = 4.162, P = 0.029) were independently related to an increased risk of rupture. Wide-necked aneurysms (OR = 0.235, P = 0.047) were independently associated with a lower risk of rupture.
conclusionsAmong pediatric patients, age younger than 5 years and lesions located in the DAR are independent risk factors for IA rupture, while an IA with a wide neck acts as a protective factor.
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