ReviewAesthetic plastic surgery2022
Adjuvant Radiotherapy for Keloids.
Review in Aesthetic plastic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Surgical Excision with Adjuvant Therapies in the Management of Keloids: A Systematic Review.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Should We Do Postoperative Radiotherapy After Keloid Excision as Soon as Possible? A Systematic Review and Meta-Analysis.Aesthetic plastic surgery · 2025Pooled it
- Prospective Study of Intense Pulsed Light With Postoperative Radiotherapy for Keloids in Young and Middle-Aged Men.Journal of cosmetic dermatology · 2025Trial
- Comparison of the biological effects of various radiation therapies for keloids by single-cell RNA sequencing reveals IRF1 as a novel target in keloid therapy.Fundamental research · 2026Article
- Application of Brachytherapy in Postoperative Treatment of Keloid-Prone Patients.Journal of cosmetic dermatology · 2026Article
- Punch Excision Combined With Radiotherapy for Keloid Treatment.Journal of cosmetic dermatology · 2026Article
- Efficacy and Safety of Punch Excision Combined With Adjuvant Therapies for Hypertrophic Scars and Keloids: A Narrative Review.Journal of cosmetic dermatology · 2026Review
- Deciphering the cellular landscape of pathological scars.Burns & trauma · 2026Article
- Multimodal ultrasound assessment for monitoring keloid severity and treatment response.Scientific reports · 2025Observational
- Treatment outcomes of surgery followed by short-course every other day radiotherapy in keloid.Radiation oncology (London, England) · 2024Article
- Pharmacotherapy for Keloids and Hypertrophic Scars.International journal of molecular sciences · 2024Review
- Surgery and superficial x-ray radiotherapy for keloids of the preauricular and contralateral ear lobe: Case report.Clinical case reports · 2024Article
- Post-operative KEloids iRradiation (POKER): does the surgery/high-dose interventional radiotherapy association make a winning hand?La Radiologia medica · 2024Article
- Inhibition of keloid byAging · 2023Article
- FBXL6 is dysregulated in keloids and promotes keloid fibroblast growth by inducing c-Myc expression.International wound journal · 2023Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Radiotherapy is one of the therapeutic methods for keloids, and the irradiation technique has innovated from superficial X-ray to brachytherapy after decades of clinical practice. At present, the application of adjuvant radiotherapy has been widely accepted by clinicians, while the consensus of optimal adjuvant radiotherapy strategies for keloids has not been reached. Factors such as radiation timing, dose, fractions, and lesion locations may be associated with the clinical outcomes of patients with keloids after radiotherapy while a comprehensive review is lacking. Herein, this review summarized the published literature of adjuvant radiotherapy for keloids involving mechanism, timing, dose, fractions, and complications, etc., which may facilitate clinical decision making.Level of Evidence III This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.