Evidence map›Paper›PMID 34415237›Full record

ArticleGlobal health action2021

Detection of Rift Valley Fever virus inter-epidemic activity in Kilimanjaro Region, North Eastern Tanzania.

Medard S Kumalija, Jaffu O Chilongola, Rule M Budodo, Pius G Horumpende, Sixbert I Mkumbaye, John-Mary Vianney, Richard S Mwakapuja, Blandina T Mmbaga

Open access · goldAbstract read
In one paragraph

Article in Global health action, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Medard S KumalijaDepartment of Global Health and Biomedical Sciences, Nelson Mandela Institution of Science and Technology, Arusha, Tanzania.ORCID 0000-0003-2696-5663
Jaffu O ChilongolaDepartment of Medical Biochemistry and Molecular Biology, Kilimanjaro Christian Medical University College, Moshi Tanzania.ORCID 0000-0003-2997-6747
Rule M BudodoDepartment of Clinical Trials, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
Pius G HorumpendeDepartment of Public Health and Research, Lugalo Military College of Medical Sciences, Dar Es Salaam, Tanzania.ORCID 0000-0003-1241-6997
Sixbert I MkumbayeDepartment of Clinical Trials, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.ORCID 0000-0001-8541-3848
John-Mary VianneyDepartment of Global Health and Biomedical Sciences, Nelson Mandela Institution of Science and Technology, Arusha, Tanzania.ORCID 0000-0001-9405-1260
Richard S MwakapujaDepartment of Bacterial Vaccines, Tanzania Veterinary Laboratory Agency (TVLA), Kibaha, Tanzania.ORCID 0000-0003-2799-8475
Blandina T MmbagaDepartment of Clinical Trials, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.ORCID 0000-0002-5550-1916
Clinical Research Institute · USNelson Mandela African Institution of Science and Technology · TZCollege of Medical Sciences · NPTanzania Meteorological Agency · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRift Valley Fever virus (RVFV) is a zoonotic arbovirus of public health impact infecting livestock, wildlife, and humans mainly in Africa and other parts of the world. Despite its public health importance, mechanisms of RVFV maintenance during interepidemic periods (IEPS) remain unclear.

objectiveWe aimed to examine comparatively exposure to RVFV between humans and goats and RVFV infection between humans, goats and mosquitoes.

methodsA cross sectional study was performed in the Lower Moshi area of the Kilimanjaro region from March to June 2020. RVFV exposure was determined by detecting IgG/IgM to RVFV using a competitive enzyme linked immunosorbent assay whereas infection was determined by real time quantitative polymerase chain reaction (RT-qPCR) assay.

resultsResults show that the male gender was related to RVFV seropositivity (χ

conclusionOur findings suggest the Lower Moshi area as a potential hotspot for Rift Valley Fever (RVF), posing the danger of being a source of RVFV spread to other areas. Goats had the highest infection rate, suggesting goats as important hosts for virus maintenance during IEPs. We recommend the implementation of strategies that will warrant active RVF surveillance through the identification of RVF hotspots for targeted control of the disease.

Indexed as

EpidemicsRift Valley FeverRift Valley fever virusAnimalsAntibodies, ViralCross-Sectional StudiesHumansMaleSeroepidemiologic StudiesTanzaniaAntibodies, ViralEpidemiologyinter-epidemicRift Valley FeverseroprevalenceTanzania

Identifiers

PMID34415237
PMCPMC8381910
OpenAlexW3194075819

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.