Evidence map›Paper›PMID 34415211›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2021

Evaluation of single bolus, dual-echo dynamic susceptibility contrast MRI protocols in brain tumor patients.

Ashley M Stokes, Maurizio Bergamino, Lea Alhilali, Leland S Hu, John P Karis, Leslie C Baxter, Laura C Bell, C Chad Quarles

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

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  13. Sinusoidal COFrontiers in physiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ashley M StokesDivision of Neuroimaging Research, Barrow Neurological Institute, Phoenix, AZ, USA.ORCID 0000-0003-1137-5003
Maurizio BergaminoDivision of Neuroimaging Research, Barrow Neurological Institute, Phoenix, AZ, USA.
Lea AlhilaliNeuroradiology, Southwest Neuroimaging at Barrow Neurological Institute, Phoenix, AZ, USA.
Leland S HuDepartment of Radiology, Division of Neuroradiology, Mayo Clinic Arizona, Phoenix, AZ, USA.
John P KarisNeuroradiology, Southwest Neuroimaging at Barrow Neurological Institute, Phoenix, AZ, USA.
Leslie C BaxterDivision of Neuroimaging Research, Barrow Neurological Institute, Phoenix, AZ, USA.
Laura C BellDivision of Neuroimaging Research, Barrow Neurological Institute, Phoenix, AZ, USA.ORCID 0000-0001-8164-8324
C Chad QuarlesDivision of Neuroimaging Research, Barrow Neurological Institute, Phoenix, AZ, USA.
Barrow Neurological Institute · USMayo Clinic Hospital · US

Funding

Quantifying Multiscale Competitive Landscapes of Clonal Diversity in GlioblastomaU01CA220378 · NCI · MAYO CLINIC ARIZONA · PI HU, LELAND, SWANSON, KRISTIN R · 2017 to 2021
$4.3M
MRI Assessment of Tumor Perfusion, Permeability and CellularityR01CA158079 · NCI · VANDERBILT UNIVERSITY · PI QUARLES, CHRISTOPHER CHAD · 2011 to 2021
$3.5M
Establishing the Validity of Brain Tumor Perfusion ImagingR01CA213158 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Christopher Chad Quarles · 2017 to 2026
$2.9M
Multi-site Validation and Application of a Consensus DSC MRI ProtocolR01CA221938 · NCI · ST. JOSEPH'S HOSPITAL AND MEDICAL CENTER · PI BOXERMAN, JERROLD L, HU, LELAND · 2018 to 2020
$738k
MRI-based mapping of regional genomic diversity in GlioblastomaR21NS082609 · NINDS · MAYO CLINIC ARIZONA · PI HU, LELAND · 2013 to 2014
$525k
NCI NIH HHS R01 CA158079NCI NIH HHS R01 CA213158NCI NIH HHS R01 CA221938NCI NIH HHS U01 CA220378NINDS NIH HHS R21 NS082609
6 · The paper itself

Abstract

Relative cerebral blood volume (rCBV) obtained from dynamic susceptibility contrast (DSC) MRI is adversely impacted by contrast agent leakage in brain tumors. Using simulations, we previously demonstrated that multi-echo DSC-MRI protocols provide improvements in contrast agent dosing, pulse sequence flexibility, and rCBV accuracy. The purpose of this study is to assess the

Indexed as

Brain NeoplasmsCerebral Blood VolumeCerebrovascular CirculationMagnetic Resonance ImagingAdultAgedAged, 80 and overContrast MediaFemaleHumansMaleMiddle AgedRetrospective StudiesContrast MediaBrain tumorsdual-echodynamic susceptibility contrast (DSC)perfusionpermeability

Identifiers

PMID34415211
PMCPMC8669280
OpenAlexW3195345186

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.