Evidence map›Paper›PMID 34415188›Full record

Trial reportAmerican journal of physiology. Heart and circulatory physiology2021

ET

Leena N Shoemaker, Katherine M Haigh, Andrew V Kuczmarski, Shane J McGinty, Laura M Welti, Joshua C Hobson, David G Edwards, Ronald F Feinberg, Megan M Wenner

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in American journal of physiology. Heart and circulatory physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Adipocyte-specific ETPhysiological reports · 2025
    Article
  5. ET(-1) phone home: a commentary on the complexities of cardiovascular disease risk in postmenopausal women.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Guidelines on the use of sex and gender in cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Leena N ShoemakerDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.
Katherine M HaighSchool of Nursing, University of Delaware, Newark, Delaware.
Andrew V KuczmarskiDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.
Shane J McGintyDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.ORCID 0000-0002-1784-9815
Laura M WeltiDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.ORCID 0000-0002-6721-5386
Joshua C HobsonDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.
David G EdwardsDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.ORCID 0000-0002-5098-6678
Ronald F FeinbergReproductive Associates of Delaware, Newark, Delaware.
Megan M WennerDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware.ORCID 0000-0003-0055-783X
University of Delaware · USReproductive Medicine Associates of New Jersey · US

Funding

Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Megan M Wenner · 2013 to 2026
$60.5M
Vascular Consequences of Duchenne Muscular DystrophyP20GM113125 · NIGMS · UNIVERSITY OF DELAWARE · PI LENNON, SHANNON L. · 2016 to 2025
$23.3M
Mechanisms of Vascular Dysfunction with Advancing Reproductive AgeR01HL146558 · NHLBI · UNIVERSITY OF DELAWARE · PI WENNER, MEGAN M · 2019 to 2023
$2.3M
American Heart Association-American Stroke Association 16SDG30700015HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL R01 146558HHS | NIH | National Institute of General Medical Sciences (NIGMS) U54-GM104941NHLBI NIH HHS R01 HL146558NIGMS NIH HHS P20 GM113125NIGMS NIH HHS U54 GM104941
6 · The paper itself

Abstract

The endothelin-B (ET

Indexed as

VasodilationAdultEndothelin B Receptor AntagonistsEstradiolEstrogensFemaleGonadotropin-Releasing HormoneHormone AntagonistsHumansMicrovesselsOligopeptidesPiperidinesReceptor, Endothelin BSkinBQ 788Endothelin B Receptor AntagonistsEstradiolEstrogensganirelixGonadotropin-Releasing HormoneHormone AntagonistsOligopeptidesPiperidinesReceptor, Endothelin Bcutaneous microdialysisendothelin-B receptorsex hormonesskin blood flow

Identifiers

PMID34415188
PMCPMC8461841
OpenAlexW3194977930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.