Evidence map›Paper›PMID 34415115›Full record

ArticleAdvanced healthcare materials2021

Manganese Ferrite Nanoparticles Encapsulated into Vitamin E/Sphingomyelin Nanoemulsions as Contrast Agents for High-Sensitive Magnetic Resonance Imaging.

Sandra Díez-Villares, Miguel A Ramos-Docampo, Andrés da Silva-Candal, Pablo Hervella, Abi J Vázquez-Ríos, Ana B Dávila-Ibáñez, Rafael López-López, Ramón Iglesias-Rey, Verónica Salgueiriño, María de la Fuente

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Contrast Agents for Enhanced Bioimaging: A Comprehensive Review.Chembiochem : a European journal of chemical biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sandra Díez-VillaresNano-Oncology and Translational Therapeutics Group, Health Research Institute of Santiago de Compostela (IDIS), SERGAS, Santiago de Compostela, 15706, Spain.ORCID 0000-0002-3311-7710
Miguel A Ramos-DocampoDepartamento de Física Aplicada, Universidade de Vigo, Vigo, 36310, Spain.ORCID 0000-0002-2714-0164
Andrés da Silva-CandalClinical Neurosciences Research Laboratory, Health Research Institute of Santiago de Compostela (IDIS), SERGAS, Santiago de Compostela, 15706, Spain.ORCID 0000-0001-5014-2224
Pablo HervellaClinical Neurosciences Research Laboratory, Health Research Institute of Santiago de Compostela (IDIS), SERGAS, Santiago de Compostela, 15706, Spain.ORCID 0000-0003-1249-6333
Abi J Vázquez-RíosNano-Oncology and Translational Therapeutics Group, Health Research Institute of Santiago de Compostela (IDIS), SERGAS, Santiago de Compostela, 15706, Spain.ORCID 0000-0002-5345-3682
Ana B Dávila-IbáñezRoche-CHUS Joint-Unit, Translational Medical Oncology Group, Health Research Institute of Santiago de Compostela (IDIS), SERGAS, Santiago de Compostela, 15706, Spain.ORCID 0000-0002-9906-5458
Rafael López-LópezBiomedical Research Networking Center on Oncology (CIBERONC), Madrid, 28029, Spain.ORCID 0000-0003-1315-655X
Ramón Iglesias-ReyClinical Neurosciences Research Laboratory, Health Research Institute of Santiago de Compostela (IDIS), SERGAS, Santiago de Compostela, 15706, Spain.ORCID 0000-0002-9985-9135
Verónica SalgueiriñoDepartamento de Física Aplicada, Universidade de Vigo, Vigo, 36310, Spain.ORCID 0000-0002-9396-468X
María de la FuenteNano-Oncology and Translational Therapeutics Group, Health Research Institute of Santiago de Compostela (IDIS), SERGAS, Santiago de Compostela, 15706, Spain.ORCID 0000-0003-0322-1469

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic resonance imaging (MRI) is one of the most powerful non-invasive imaging modalities used in clinics due to its great spatial resolution and excellent soft-tissue contrast, though still less sensitive than other techniques such as the nuclear imaging modalities. This lack of sensitivity can be improved with the use of contrast agents based on nanomaterials. In recent years, researchers have focused on the development of magnetic nanoparticles, given their role as enhancers of the contrast signal based on the magnetic resonance. Manganese ferrite nanoparticles stand out, given their high magnetic susceptibility and magnetic soft nature. Herein, 10 nm MnFe

Indexed as

Contrast MediaNanoparticlesFerric CompoundsMagnetic Resonance ImagingManganese CompoundsSphingomyelinsVitamin EContrast MediaFerric CompoundsManganese Compoundsmanganese ferriteSphingomyelinsVitamin Emagnetic resonance imagingnanoemulsionssphingomyelinsuperparamagnetic manganese-ferrite nanoparticlestransverse relaxivityvitamin E

Identifiers

PMID34415115
PMCPMC11469163

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.