Evidence map›Paper›PMID 34414800›Full record

ArticleGlobal spine journal2023

Perioperative Factors Associated With Chronic Opioid Use After Spine Surgery.

Eric Y Montgomery, Mark N Pernik, Zachary D Johnson, Luke J Dosselman, Zachary K Christian, Palvasha R Deme, Emmanuel A Adeyemo, Umaru Barrie, Olatunde Badejo, Nick A Stewart and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Global spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07777679 (A Randomized Controlled Pilot Trial Evaluating Virtual Reality-Based Cognitive Behavioral Therapy), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07777679 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Randomized Controlled Pilot Trial Evaluating Virtual Reality-Based Cognitive Behavioral Therapy (VR-CBT) as a Prehabilitation Intervention for Adult Spinal Deformity Surgery

TypeinterventionalSponsorUniversity of California, IrvineRan2026 to 2028Enrolled80ConditionsDegenerative Spine Disease, Spinal Stenosis LumbarArmsVirtual Reality-Based CBT Prehabilitation (VR-CBT), CBT Prehabilitation without Virtual Reality
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The association between postoperative physical therapy and opioid prescription after posterior lumbar interbody fusion: a retrospective cohort study of United States academic health centers.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  6. Article
  7. Observational
  8. Observational
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Eric Y MontgomeryDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.ORCID 0000-0001-8255-2455
Mark N PernikDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.ORCID 0000-0002-7568-7308
Zachary D JohnsonDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.
Luke J DosselmanDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.
Zachary K ChristianDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.
Palvasha R DemeDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.
Emmanuel A AdeyemoDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.
Umaru BarrieDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.ORCID 0000-0002-0365-7070
Olatunde BadejoDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.
Nick A StewartDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.
Ruta UttarkarDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.
Owoicho AdogwaDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.
Najib El TecleDepartment of Neurological Surgery, Saint Louis University School of Medicine, MO, USA.
Salah G AounDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.ORCID 0000-0003-3499-7569
Carlos A BagleyDepartment of Neurological Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective case control.

objectivesThe purpose of the current study is to determine risk factors associated with chronic opioid use after spine surgery.

methodsIn our single institution retrospective study, 1,299 patients undergoing elective spine surgery at a tertiary academic medical center between January 2010 and August 2017 were enrolled into a prospectively collected registry. Patients were dichotomized based on renewal of, or active opioid prescription at 3-mo and 12-mo postoperatively. The primary outcome measures were risk factors for opioid renewal 3-months and 12-months postoperatively. These primarily included demographic characteristics, operative variables, and in-hospital opioid consumption via morphine milligram equivalence (MME). At the 3-month and 12-month periods, we analyzed the aforementioned covariates with multivariate followed by bivariate regression analyses.

resultsMultivariate and bivariate analyses revealed that script renewal at 3 months was associated with black race (

conclusionThe current study describes multiple patient-level factors associated with chronic opioid use. Notably, no metric of perioperative opioid utilization was directly associated with chronic opioid use after multivariate analysis.

Indexed as

addictionchronic painnarcotic renewalopioid usepostoperative narcoticspine surgery

Identifiers

PMID34414800
PMCPMC10448093

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.