Evidence map›Paper›PMID 34414798›Full record

ArticleThe American journal of hospice & palliative care2022

Clinician Ethical Perspectives on Extracorporeal Membrane Oxygenation in Practice.

Gina M Piscitello, Rene S Bermea, John W Stokes, Whitney D Gannon, Anthony J Kanelidis, Megan Konopka, Claire Shappell, Laura K Frye, Patrick G Lyons, Mark Siegler and 1 more

Open access · greenAbstract read
In one paragraph

Article in The American journal of hospice & palliative care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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  8. [Extracorporeal life support (ECLS): 2021 update].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2022
    Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Gina M PiscitelloDepartment of Medicine, Rush Medical College, Chicago, IL, USA.ORCID https://orcid.org/0000-0002-3958-4491
Rene S BermeaDivision of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, USA.
John W StokesDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Whitney D GannonDepartment of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Anthony J KanelidisSection of Cardiology, University of Chicago, Chicago, IL, USA.
Megan KonopkaDivision of Pulmonary and Critical Care Medicine, Rush University Medical Center, Chicago, IL, USA.
Claire ShappellDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Laura K FryeDivision of Allergy, Pulmonary, and Critical Care Medicine, University of Wisconsin, Madison, WI, USA.
Patrick G LyonsDivision of Pulmonary and Critical Care Medicine, Washington University in St. Louis, MO, USA.
Mark SieglerDepartment of Medicine, University of Chicago, IL, USA.
William F ParkerMacLean Center for Clinical Medical Ethics, University of Chicago, IL, USA.
University of Chicago · USRush University Medical Center · USVanderbilt University Medical Center · USBrigham and Women's Hospital · USMassachusetts General Hospital · USUniversity of Wisconsin–Madison · USWashington University in St. Louis · US

Funding

Research Training in Pulmonary Immunology and Allergy at MGHT32HL116275 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI David C Christiani, ANDREW D LUSTER · 2013 to 2026
$8.6M
Mending a Broken Heart Allocation System with Machine LearningK08HL150291 · NHLBI · UNIVERSITY OF CHICAGO · PI PARKER, WILLIAM F · 2020 to 2024
$713k
NHLBI NIH HHS K08 HL150291NHLBI NIH HHS T32 HL116275
6 · The paper itself

Abstract

purposeExtracorporeal membrane oxygenation (ECMO) is an expensive and scarce life sustaining treatment provided to certain critically ill patients. Little is known about the informed consent process for ECMO or clinician viewpoints on ethical complexities related to ECMO in practice.

methodsWe sent a cross-sectional survey to all departments providing ECMO within 7 United States hospitals in January 2021. One clinician from each department completed the 42-item survey representing their department.

resultsFourteen departments within 7 hospitals responded (response rate 78%, N = 14/18). The mean time spent consenting patients or surrogate decision-makers for ECMO varied, from 7.5 minutes (95% CI 5-10) for unstable patients to 20 minutes (95% CI 15-30) for stable patients (p = 0.0001). Few clinician respondents (29%) report patients or surrogate decision-makers always possess informed consent for ECMO. Most departments (92%) have absolute exclusion criteria for ECMO such as older age (43%, cutoffs ranging from 60-75 years), active malignancy (36%), and elevated body mass index (29%). A significant minority of departments (29%) do not always offer the option to withdraw ECMO to patients or surrogate decision-makers. For patients who cannot be liberated from ECMO and are ineligible for heart or lung transplant, 36% of departments would recommend the patient be removed from ECMO and 64% would continue ECMO support.

conclusionAdequate informed consent for ECMO is a major ethical challenge, and the content of these discussions varies. Use of categorical exclusion criteria and withdrawal of ECMO if a patient cannot be liberated from it differ among departments and institutions.

Indexed as

Extracorporeal Membrane OxygenationCritical IllnessCross-Sectional StudiesHumansRetrospective StudiesSurveys and QuestionnairesUnited Statesethicsextracorporeal membrane oxygenationinformed consentwithdrawal of life-sustaining treatment

Identifiers

PMID34414798
PMCPMC8858336
OpenAlexW3195297105

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.