Evidence map›Paper›PMID 34414699›Full record

ReviewJournal of Zhejiang University. Science. B2021

LG-ESSs and HG-ESSs: underlying molecular alterations and potential therapeutic strategies.

Chunhui Li, Chunhong Wang

Open access · greenAbstract readReview
In one paragraph

Review in Journal of Zhejiang University. Science. B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Current Treatment Options: Uterine Sarcoma.Current treatment options in oncology · 2024
    Review
  6. Article
  7. Article
  8. Uterine tumor resembling high-grade endometrial mesenchymal sarcoma with GATAD2B-MMRN1 fusion.International journal of clinical and experimental pathology · 2023
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chunhui LiQuality Management Office, The Second Hospital of Jilin University, Changchun 130041, China.
Chunhong WangDepartment of Hematology and Oncology, The Second Hospital of Jilin University, Changchun 130041, China. wang_ch@jlu.edu.cn.
Second Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometrial stromal tumors (ESTs) include endometrial stromal nodule (ESN), low-grade endometrial stromal sarcoma (LG-ESS), high-grade endometrial stromal sarcoma (HG-ESS), and undifferentiated uterine sarcoma (UUS). Since these are rare tumor types, there is an unmet clinical need for the systematic therapy of advanced LG-ESS or HG-ESS. Cytogenetic and molecular advances in ESTs have shown that multiple recurrent gene fusions are present in a large proportion of LG-ESSs, and HG-ESSs are identified by the tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon (

Indexed as

14-3-3 ProteinsCarcinogenesisEndometrial NeoplasmsEndometrial Stromal TumorsFemaleGene DuplicationHumansOncogene Proteins, FusionProto-Oncogene ProteinsRepressor ProteinsRNA-Binding ProteinsSarcoma, Endometrial StromalSignal Transduction14-3-3 ProteinsBCOR protein, humanOncogene Proteins, FusionProto-Oncogene ProteinsRepressor ProteinsRNA-Binding ProteinsYWHAE protein, humanZC3H7B protein, humanHigh-grade endometrial stromal sarcoma (HG-ESS)Low-grade endometrial stromal sarcoma (LG-ESS)Molecular geneticsTherapeutics

Identifiers

PMID34414699
PMCPMC8377580
OpenAlexW3194057929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.