ArticleCancer medicine2021
Association between socioeconomic status and survival in patients with hepatocellular carcinoma.
Article in Cancer medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Sex and gender disparities in hepatocellular carcinoma: insights into risk, diagnosis, and therapeutic outcomes.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Review
- Nomogram prediction of overall survival in patients with bone metastases from hepatocellular carcinoma: a SEER-based retrospective cohort study.Scientific reports · 2025Article
- Determinants of Health-Related Quality of Life After Transarterial Chemoembolization in Hepatocellular Carcinoma Patients: A Systematic Review.Journal of clinical medicine · 2025Review
- Factor Analysis of the Effect of Hepatitis B-Related Liver Cancer Treatment Efficacy.Journal of hepatocellular carcinoma · 2025Article
- Incidence and survival of pediatric and adult hepatocellular carcinoma, United States, 2001-2020.Cancer epidemiology · 2024Article
- Association of county level poverty with mortality from primary liver cancers.Cancer medicine · 2024Article
- Article
- Hepatocellular Carcinoma: Prevention, Diagnosis, and Treatment.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2024Review
- How education level affects postoperative rehabilitation and follow-up: a single-center experience.BMC urology · 2023Article
- Investigating the Quality of Life for Cancer Patients and Estimating the Cost of Immunotherapy in Selected Cases.Cureus · 2022Article
- Socioeconomic deprivation and survival outcomes in primary central nervous system lymphomas.Frontiers in oncology · 2022Article
- Association between socioeconomic status and survival in patients with hepatocellular carcinoma.Cancer medicine · 2021Article
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5 authors.
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Abstract
backgroundThe effect of socioeconomic status (SES) on hepatocellular carcinoma (HCC) is still unclear, and there is no nomogram integrated SES and clinicopathological factors to predict the prognosis of HCC. This research aims to confirm the effects of SES on predicting patients' survival and to establish a nomogram to predict the prognosis of HCC.
methodsThe data of HCC patients were collected from the Surveillance, Epidemiology, and Final Results (SEER) database from 2011 to 2015. SES (age at diagnosis, race and sex, median family income, education level, insurance status, marital status, residence, cost of living index, poverty rate) and clinicopathological factors were included in univariate and multivariate Cox regression analysis. Nomograms for predicting 1-, 3-, and 5-year cancer-specific survival (CSS) and overall survival (OS) were established and evaluated by the concordance index (C-index), the receiver operating characteristic curve (ROC), the calibration plot, the integrated discrimination improvement (IDI), and the net reclassification improvement (NRI).
resultsA total of 33,670 diagnosed HCC patients were involved, and nomograms consisting of 19 variables were established. The C-indexes of the nomograms are higher than TNM staging system, which predicts the CSS (0.789 vs. 0.692, p < 0.01) and OS (0.777 vs. 0.675, p < 0.01). The ROC curve, calibration diagram, IDI, and NRI showed the improved prognostic value in 1-, 3-, and 5-year survival rates.
conclusionSES plays an important role in the prognosis of HCC patients. Therefore, policymakers can make more precise and socially approved policies to improve HCC patients' CSS and OS.
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