Evidence map›Paper›PMID 34414470›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2022

Similar patterns of [

Aurelie Morand, Jacques-Yves Campion, Anne Lepine, Emmanuelle Bosdure, Léa Luciani, Serge Cammilleri, Brigitte Chabrol, Eric Guedj

Open access · bronzeAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Molecular Imaging Findings on Acute and Long-Term Effects of COVID-19 on the Brain: A Systematic Review.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Pooled it
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  18. Effects of COVID-19 on cognition and brain health.Trends in cognitive sciences · 2023
    Review
  19. Year 2022: exploring COVID-19 pandemic in children.Italian journal of pediatrics · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Aurelie MorandService de Médecine Infantile et Pédiatrie Spécialisée, Timone Hospital, AP-HM, 13005, Marseille, France.
Jacques-Yves CampionNuclear Medicine Department, Aix Marseille Univ, APHM, CNRS, Centrale Marseille, Institut Fresnel, Timone Hospital, CERIMED, Marseille, France.
Anne LepineService de Médecine Infantile et Pédiatrie Spécialisée, Timone Hospital, AP-HM, 13005, Marseille, France.
Emmanuelle BosdureService de Médecine Infantile et Pédiatrie Spécialisée, Timone Hospital, AP-HM, 13005, Marseille, France.
Léa LucianiUnité Des Virus Émergents (UVE: Aix-Marseille Univ-IRD, 190-Inserm 1207-IHU Méditerranée Infection), Marseille, France.
Serge CammilleriNuclear Medicine Department, Aix Marseille Univ, APHM, CNRS, Centrale Marseille, Institut Fresnel, Timone Hospital, CERIMED, Marseille, France.
Brigitte ChabrolService de Médecine Infantile et Pédiatrie Spécialisée, Timone Hospital, AP-HM, 13005, Marseille, France.
Eric GuedjNuclear Medicine Department, Aix Marseille Univ, APHM, CNRS, Centrale Marseille, Institut Fresnel, Timone Hospital, CERIMED, Marseille, France. eric.guedj@ap-hm.fr.ORCID http://orcid.org/0000-0003-1912-6132
Assistance Publique Hôpitaux de Marseille · FRCentre National de la Recherche Scientifique · FRInserm · FRMéditerranée Infection Foundation · FR

Funding

aphm PHRC 07 09
6 · The paper itself

Abstract

purposeSeveral weeks after COVID-19 infection, some children report the persistence or recurrence of functional complaints. This clinical presentation has been referred as "long COVID" in the adult population, and an [

methodsReview of clinical examination and whole-brain voxel-based analysis of [

resultsDespite lower initial severity at the acute stage of the infection, paediatric patients demonstrated on average 5 months later a similar brain hypometabolic pattern as that found in adult long COVID patients, involving bilateral medial temporal lobes, brainstem and cerebellum (p-voxel < 0.001, p-cluster < 0.05 FWE-corrected), and also the right olfactory gyrus after small volume correction (p-voxel = 0.010 FWE-corrected), with partial PET recovery in two children at follow-up.

conclusionThese results provide arguments in favour of possible long COVID in children, with a similar functional brain involvement to those found in adults, regardless of age and initial severity.

Indexed as

COVID-19BrainChildFluorodeoxyglucose F18HumansPositron-Emission TomographyPost-Acute COVID-19 SyndromeRetrospective StudiesSARS-CoV-2Fluorodeoxyglucose F18ChildrenCognitionComplaintsFatigueSARS-CoV-2

Identifiers

PMID34414470
PMCPMC8376118
OpenAlexW3186754648

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.