Evidence map›Paper›PMID 34414404›Full record

ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2020

CircleNet: Anchor-free Glomerulus Detection with Circle Representation.

Haichun Yang, Ruining Deng, Yuzhe Lu, Zheyu Zhu, Ye Chen, Joseph T Roland, Le Lu, Bennett A Landman, Agnes B Fogo, Yuankai Huo

Abstract read
In one paragraph

Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Cross-organ Deployment of EOS Detection AI without Retraining: Feasibility and Limitation.Proceedings of SPIE--the International Society for Optical Engineering · 2025
    Article
  4. Weighted Circle Fusion: Ensembling Circle Representation from Different Object Detection Results.Proceedings of SPIE--the International Society for Optical Engineering · 2025
    Article
  5. Review
  6. Eosinophils Instance Object Segmentation on Whole Slide Imaging Using Multi-label Circle Representation.Proceedings of SPIE--the International Society for Optical Engineering · 2024
    Article
  7. An End-to-end Pipeline for 3D Slide-wise Multi-stain Renal Pathology Registration.Proceedings of SPIE--the International Society for Optical Engineering · 2023
    Article
  8. Article
  9. Article
  10. A semi-supervised learning framework for micropapillary adenocarcinoma detection.International journal of computer assisted radiology and surgery · 2022
    Article
  11. Circle Representation for Medical Object Detection.IEEE transactions on medical imaging · 2022
    Article
  12. Article
  13. Article
  14. AI applications in renal pathology.Kidney international · 2021
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Haichun YangVanderbilt University Medical Center, Nashville TN 37215, USA.
Ruining DengVanderbilt University, Nashville TN 37215, USA.
Yuzhe LuVanderbilt University, Nashville TN 37215, USA.
Zheyu ZhuVanderbilt University, Nashville TN 37215, USA.
Ye ChenVanderbilt University, Nashville TN 37215, USA.
Joseph T RolandVanderbilt University Medical Center, Nashville TN 37215, USA.
Le LuPAII Inc., Bethesda MD 20817, USA.
Bennett A LandmanVanderbilt University, Nashville TN 37215, USA.
Agnes B FogoVanderbilt University Medical Center, Nashville TN 37215, USA.
Yuankai HuoVanderbilt University, Nashville TN 37215, USA.

Funding

RESOLUTION OF GLOMERULOSCLEROSISR01DK056942 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI FOGO, AGNES B. · 2001 to 2021
$4.9M
NIDDK NIH HHS R01 DK056942
6 · The paper itself

Abstract

Object detection networks are powerful in computer vision, but not necessarily optimized for biomedical object detection. In this work, we propose CircleNet, a simple anchor-free detection method with circle representation for detection of the ball-shaped glomerulus. Different from the traditional bounding box based detection method, the bounding circle (1) reduces the degrees of freedom of detection representation, (2) is naturally rotation invariant, (3) and optimized for ball-shaped objects. The key innovation to enable this representation is the anchor-free framework with the circle detection head. We evaluate CircleNet in the context of detection of glomerulus. CircleNet increases average precision of the glomerulus detection from 0.598 to 0.647. Another key advantage is that CircleNet achieves better rotation consistency compared with bounding box representations.

Indexed as

Anchor-freeCircleNetDetectionPathology

Identifiers

PMID34414404
PMCPMC8372751

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.