Evidence map›Paper›PMID 34414399›Full record

ArticleArchives of autoimmune diseases2020

Adiponectin receptor fragmentation in mouse models of type 1 and type 2 diabetes.

Dylan Frabutt, Natalie Stull, Annie R Pineros, Sarah A Tersey, Donalyn Scheuner, Teresa L Mastracci, Michael J Pugia

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of autoimmune diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Dylan FrabuttIndiana Biosciences Research Institute, Indianapolis IN, United States.
Natalie StullIndiana Biosciences Research Institute, Indianapolis IN, United States.
Annie R PinerosCenter for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis IN, United States.
Sarah A TerseyCenter for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis IN, United States.
Donalyn ScheunerIndiana Biosciences Research Institute, Indianapolis IN, United States.
Teresa L MastracciIndiana Biosciences Research Institute, Indianapolis IN, United States.
Michael J PugiaIndiana Biosciences Research Institute, Indianapolis IN, United States.
Indiana Biosciences Research Institute · USIndiana University School of MedicineIndiana University – Purdue University Indianapolis · US

Funding

The 12-HETE receptor Gpr31 in the -cell pathogenesis of type 1 diabetesR03TR003381 · NCATS · UNIVERSITY OF CHICAGO · PI MIRMIRA, RAGHAVENDRA G, TERSEY, SARAH A. · 2020 to 2020
$162k
NCATS NIH HHS R03 TR003381
6 · The paper itself

Abstract

The protein hormone adiponectin regulates glucose and fatty acid metabolism by binding to two PAQR-family receptors (AdipoR1 and AdipoR2). Both receptors feature a C-terminal segment which is released by proteolysis to form a freely circulating C-terminal fragment (CTF) found in the plasma of normal individuals but not in some undefined diabetes patients. The AdipoR1-CTF

Identifiers

PMID34414399
PMCPMC8372748
OpenAlexW3193648176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.