Evidence map›Paper›PMID 34414380›Full record

ArticleCell reports. Physical science2020

Direct Photon-by-Photon Analysis of Time-Resolved Pulsed Excitation Data using Bayesian Nonparametrics.

Meysam Tavakoli, Sina Jazani, Ioannis Sgouralis, Wooseok Heo, Kunihiko Ishii, Tahei Tahara, Steve Pressé

Abstract read
In one paragraph

Article in Cell reports. Physical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  4. Article
  5. Resolving Molecular Heterogeneity with Single-Molecule Centrifugation.Journal of the American Chemical Society · 2023
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Meysam TavakoliDepartment of Physics, Indiana University-Purdue University, Indianapolis, IN 46202, USA.
Sina JazaniCenter for Biological Physics, Department of Physics, Arizona State University, Tempe, AZ 85287, USA.
Ioannis SgouralisCenter for Biological Physics, Department of Physics, Arizona State University, Tempe, AZ 85287, USA.
Wooseok HeoMolecular Spectroscopy Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Kunihiko IshiiMolecular Spectroscopy Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Tahei TaharaMolecular Spectroscopy Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Steve PresséCenter for Biological Physics, Department of Physics, Arizona State University, Tempe, AZ 85287, USA.

Funding

A Bayesian nonparametric approach to superresolved tracking of multiple molecules inside living cellsR01GM130745 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI PRESSE, STEVE · 2019 to 2023
$1.5M
Theoretical Models of Single Molecule Dynamics from Minimal Photon NumbersR01GM134426 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI PRESSE, STEVE · 2019 to 2022
$1.2M
NIGMS NIH HHS R01 GM130745NIGMS NIH HHS R01 GM134426
6 · The paper itself

Abstract

Lifetimes of chemical species are typically estimated by either fitting time-correlated single-photon counting (TCSPC) histograms or phasor analysis from time-resolved photon arrivals. While both methods yield lifetimes in a computationally efficient manner, their performance is limited by choices made on the number of distinct chemical species contributing photons. However, the number of species is encoded in the photon arrival times collected for each illuminated spot and need not be set by hand

Identifiers

PMID34414380
PMCPMC8373049

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.