Evidence map›Paper›PMID 34414379›Full record

ArticleSTAR protocols2021

Optimization of antigen-specific CD8

Chanchan Xiao, Congling Qiu, Jieping Deng, Jiezhou Ye, Lijuan Gao, Jun Su, Oscar Junhong Luo, Pengcheng Wang, Guobing Chen

Open access · goldAbstract read
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Characterizing HLA-A2-restricted CD8Frontiers in immunology · 2025
    Article
  2. Article
  3. Article
  4. From Immunogen to COVID-19 vaccines: Prospects for the post-pandemic era.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. CD8Frontiers in immunology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chanchan XiaoDepartment of Microbiology and Immunology, Institute of Geriatric Immunology, School of Medicine, Jinan University, Guangzhou, China.
Congling QiuDepartment of Microbiology and Immunology, Institute of Geriatric Immunology, School of Medicine, Jinan University, Guangzhou, China.
Jieping DengDepartment of Microbiology and Immunology, Institute of Geriatric Immunology, School of Medicine, Jinan University, Guangzhou, China.
Jiezhou YeDepartment of Microbiology and Immunology, Institute of Geriatric Immunology, School of Medicine, Jinan University, Guangzhou, China.
Lijuan GaoDepartment of Microbiology and Immunology, Institute of Geriatric Immunology, School of Medicine, Jinan University, Guangzhou, China.
Jun SuAffiliated Huaqiao Hospital, Jinan University, Guangzhou, China.
Oscar Junhong LuoGuangdong-Hong Kong-Macau Great Bay Area Geroscience Joint Laboratory, Guangzhou, China.
Pengcheng WangDepartment of Microbiology and Immunology, Institute of Geriatric Immunology, School of Medicine, Jinan University, Guangzhou, China.
Guobing ChenDepartment of Microbiology and Immunology, Institute of Geriatric Immunology, School of Medicine, Jinan University, Guangzhou, China.
Jinan University · CNFirst Affiliated Hospital of Jinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we describe the use of the artificial antigen-presenting cell (aAPC) system for the verification of T-cell epitopes. We purify and activate CD8

Indexed as

CD8-Positive T-LymphocytesCOVID-19Epitopes, T-LymphocyteHLA-A2 AntigenHumansLymphocyte ActivationSARS-CoV-2Spike Glycoprotein, CoronavirusTumor Necrosis Factor Receptor Superfamily, Member 7Epitopes, T-LymphocyteHLA-A2 AntigenSpike Glycoprotein, CoronavirusTumor Necrosis Factor Receptor Superfamily, Member 7Cell BiologyCell isolationImmunologyMicrobiology

Identifiers

PMID34414379
PMCPMC8363473
OpenAlexW3194786911

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.