ArticleEuropean stroke journal2021
European Stroke Organisation guideline on endarterectomy and stenting for carotid artery stenosis.
Article in European stroke journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 43 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 5 syntheses or guidelines pooled it, 121 citations in OpenAlex.
- Medical management and revascularization for asymptomatic carotid stenosis: a meta-analysis of randomized controlled trials.Journal of neurology · 2026Pooled it
- Temporal trends in short- and long-term outcomes after carotid interventions for symptomatic or asymptomatic stenosis: a systematic review and meta-analysis.European stroke journal · 2026Pooled it
- Carotid Artery Stenting With Double-Layer Stent: A Systematic Review and Meta-Analysis.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2024Pooled it
- Systematic Review and Meta-analysis of Radial or Femoral Access for Carotid Stenting.Clinical neuroradiology · 2024Pooled it
- [Important recommendations of the German-Austrian S3 guidelines on management of extracranial carotid artery stenosis].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2022Guideline
- Agreement across different measurements for internal carotid artery stenosis in patients with TIA or stroke in the CONVINCE trial.European radiology · 2026Trial
- Detection of serum amyloid A in Saliva of patients with internal carotid artery stenosis: a pilot study.Clinical oral investigations · 2026Article
- Carotid Artery Stenting vs Endarterectomy Across Procedural Eras : A Systematic Review and Meta-Analysis.Clinical neuroradiology · 2026Review
- Fat-suppression performance for in-stent plaque imaging after carotid artery stenting using three-dimensional TPhysical and engineering sciences in medicine · 2026Article
- Sequential contrast-enhanced ultrasound assessment of intraplaque enhancement in carotid plaques.Journal of ultrasound · 2026Article
- Endovascular management of tandem occlusions: current evidence and future directions.Journal of neurointerventional surgery · 2026Review
- Predictive factors for postoperative cerebral infarction after carotid endarterectomy and stenting: A single-center experience from 199 consecutive cases.Neurosurgical review · 2025Article
- Photon-counting detector CT angiography to evaluate carotid and subclavian artery stents and compared to ultrasound and angiography - an in-vivo study with spectral reconstructions.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Transradial access with Simmons guiding catheter for carotid artery stenting: Feasibility and procedural complications in a single-center experience.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Post-Radiotherapy Carotid Stenosis in a Patient With Head and Neck Cancer: A Case Report.Cureus · 2025Article
- [Stenting of the extracranial internal carotid artery].Innere Medizin (Heidelberg, Germany) · 2025Review
- CYP2C19 Genotype-Guided Antiplatelet Therapy and Clinical Outcomes in Patients Undergoing a Neurointerventional Procedure.Clinical and translational science · 2025Review
- Unmasking the hidden culprit: Recurrent syncope in a 62-year-old man linked to severe internal carotid artery stenosis.Radiology case reports · 2025Article
- Operative Factors Associated with Severe Hypotension in the Postoperative Setting in Patients with Carotid Artery Endarterectomy.Life (Basel, Switzerland) · 2024Article
- Aphasia due to right hemisphere infarction in a patient with situs inversus after carotid artery stenting: a case report.BMC neurology · 2024Article
Corrections and comments
- Retraction · 2021-11-11Duplication of Content through Error by Journal/Publisher · Removed ·
- Retracted
Authors and funding
14 authors at 12 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atherosclerotic stenosis of the internal carotid artery is an important cause of stroke. The aim of this guideline is to analyse the evidence pertaining to medical, surgical and endovascular treatment of patients with carotid stenosis. These guidelines were developed based on the ESO standard operating procedure and followed the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. The working group identified relevant questions, performed systematic reviews and meta-analyses of the literature, assessed the quality of the available evidence, and wrote recommendations. Based on moderate quality evidence, we recommend carotid endarterectomy (CEA) in patients with ≥60-99% asymptomatic carotid stenosis considered to be at increased risk of stroke on best medical treatment (BMT) alone. We also recommend CEA for patients with ≥70-99% symptomatic stenosis, and we suggest CEA for patients with 50-69% symptomatic stenosis. Based on high quality evidence, we recommend CEA should be performed early, ideally within two weeks of the last retinal or cerebral ischaemic event in patients with ≥50-99% symptomatic stenosis. Based on low quality evidence, carotid artery stenting (CAS) may be considered in patients < 70 years old with symptomatic ≥50-99% carotid stenosis. Several randomised trials supporting these recommendations were started decades ago, and BMT, CEA and CAS have evolved since. The results of another large trial comparing outcomes after CAS versus CEA in patients with asymptomatic stenosis are anticipated in the near future. Further trials are needed to reassess the benefits of carotid revascularisation in combination with modern BMT in subgroups of patients with carotid stenosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.