Evidence map›Paper›PMID 34414297›Full record

ArticleEuropean stroke journal2021

Trial design and pilot phase results of a cluster-randomised intervention trial to improve stroke care after hospital discharge - The structured ambulatory post-stroke care program (SANO).

Felizitas A Eichner, Christopher J Schwarzbach, Moritz Keller, Karl Georg Haeusler, Gerhard F Hamann, Dirk Sander, Heinrich J Audebert, Klaus Gröschel, Dieter Geis, Stephan von Bandemer and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in European stroke journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Engaging patients in designing a transmural allied health pathway: A qualitative exploration of hospital-to-home transitions.Health expectations : an international journal of public participation in health care and health policy · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 2 countries.

Felizitas A EichnerInstitute for Clinical Epidemiology and Biometry, Universität Würzburg, Würzburg, Germany.ORCID https://orcid.org/0000-0002-5415-0456
Christopher J SchwarzbachDepartment of Neurology, Klinikum der Stadt Ludwigshafen am Rhein, Ludwigshafen, Germany.
Moritz KellerDepartment of Neurology, Klinikum der Stadt Ludwigshafen am Rhein, Ludwigshafen, Germany.
Karl Georg HaeuslerDepartment of Neurology, Universitätsklinikum Würzburg, Würzburg, Germany.
Gerhard F HamannClinic for Neurology and Neurological Rehabilitation, Bezirkskrankenhaus Günzburg, Günzburg, Germany.
Dirk SanderDepartment of Neurology, Benedictus Krankenhaus Tutzing, Tutzing, Germany.
Heinrich J AudebertDepartment of Neurology with Experimental Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Klaus GröschelDepartment of Neurology, Universitätsmedizin Mainz, Mainz, Germany.ORCID https://orcid.org/0000-0002-0244-6116
Dieter GeisBayrischer Hausärzteverband, München, Germany.
Stephan von BandemerInstitute for Work and Technology, Ruhr Universität Bochum, Bochum, Germany.
Viktoria RückerInstitute for Clinical Epidemiology and Biometry, Universität Würzburg, Würzburg, Germany.
Martha SchutzmeierInstitute for Clinical Epidemiology and Biometry, Universität Würzburg, Würzburg, Germany.
Peter Ulrich HeuschmannInstitute for Clinical Epidemiology and Biometry, Universität Würzburg, Würzburg, Germany.
Armin GrauDepartment of Neurology, Klinikum der Stadt Ludwigshafen am Rhein, Ludwigshafen, Germany.
SANO Study Group
Zimmer Biomet (Netherlands) · NLKlinikum Ludwigshafen · DEBerufsverband der Frauenärzte · DECharité - Universitätsmedizin Berlin · DEFachkrankenhaus Hubertusburg · DEFranziskus-Krankenhaus Berlin · DEJohannes Gutenberg University Mainz · DERuhr University Bochum · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrevious studies showed insufficient control of cardiovascular risk factors (CVRF) and high stroke recurrence rates among ischemic stroke patients in Germany. Currently, no structured secondary prevention program exists in clinical routine. We present the trial design and pilot phase results of a complex intervention to improve stroke care after hospital discharge in Germany. PATIENTS AND

methodsSANO is a cluster-randomized trial with 30 participating regions across Germany aiming to enrol 2,790 patients (drks.de, DRKS00015322). Study intervention combines both structural and patient-centred elements. Study development was based on the Medical Research Council framework for complex interventions. In 15 intervention regions, a cross-sectoral multidisciplinary network is established to enhance CVRF control as well as detection and treatment of post-stroke complications. Recommendations on CVRF are based on high-quality secondary prevention guidelines. Study physicians use motivational interviewing and agree with patients on therapeutic targets. While hospitalised, patients also receive dietary counselling and a health-passport to track their progress. During regular visits, CVRF management and potential complications are monitored. The intervention is compared to 15 regions providing usual care. The primary endpoint is the combination of recurrent stroke, myocardial infarction and death assessed 12 months after enrolment and adjudicated in a blinded manner.

resultsEighteen patients were enrolled in a pilot phase that demonstrated feasibility of patient recruitment and study procedures.

conclusionSANO is investigating a program to reduce outcome events after ischemic stroke by implementing a complex intervention. If successful, the program may be implemented in routine care on national level in Germany.

Indexed as

ischemic strokepilot phasepost-stroke complicationsprotocolrisk factorsSecondary prevention

Identifiers

PMID34414297
PMCPMC8370073
OpenAlexW3012531808

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.