Evidence map›Paper›PMID 34414295›Full record

ArticleEuropean stroke journal2021

Sensitivity of prehospital stroke scales for different intracranial large vessel occlusion locations.

Martijne Hc Duvekot, Esmee Venema, Hester F Lingsma, Jonathan M Coutinho, H Bart van der Worp, Jeannette Hofmeijer, Reinoud Ph Bokkers, Adriaan Cgm van Es, Aad van der Lugt, Henk Kerkhoff and 3 more

Open access · hybridAbstract read
In one paragraph

Article in European stroke journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Large vessel occlusion prediction scale thresholds that are sensitive for DAWN Trial patients.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Martijne Hc DuvekotDepartment of Neurology, Albert Schweitzer Hospital, Dordrecht, the Netherlands.ORCID https://orcid.org/0000-0003-0027-3669
Esmee VenemaDepartment of Neurology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Hester F LingsmaDepartment of Public Health, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Jonathan M CoutinhoDepartment of Neurology, Amsterdam University Medical Centers, Amsterdam, the Netherlands.
H Bart van der WorpDepartment of Neurology and Neurosurgery, University Medical Center Utrecht, Brain Center, Utrecht, the Netherlands.ORCID https://orcid.org/0000-0001-9891-2136
Jeannette HofmeijerDepartment of Neurology, Rijnstate Hospital, Arnhem, the Netherlands.
Reinoud Ph BokkersDepartment of Radiology, Medical Imaging Center, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Adriaan Cgm van EsDepartment of Radiology, Leiden University Medical Center, Leiden, the Netherlands.
Aad van der LugtDepartment of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Henk KerkhoffDepartment of Neurology, Albert Schweitzer Hospital, Dordrecht, the Netherlands.
Diederik Wj DippelDepartment of Neurology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Bob RoozenbeekDepartment of Neurology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
MR CLEAN Registry investigators
Erasmus MC · NLAlbert Schweitzer Ziekenhuis · NLAmsterdam University Medical Centers · NLLeiden University Medical Center · NLRijnstate Hospital · NLUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrehospital stroke scales have been proposed to identify stroke patients with a large vessel occlusion to allow direct transport to an intervention centre capable of endovascular treatment (EVT). It is unclear whether these scales are able to detect not only proximal, but also more distal treatable occlusions. Our aim was to assess the sensitivity of prehospital stroke scales for different EVT-eligible occlusion locations in the anterior circulation. PATIENTS AND

methodsThe MR CLEAN Registry is a prospective, observational study in all centres that perform EVT in the Netherlands. We included adult patients with an anterior circulation stroke treated between March 2014 and November 2017. We used National Institutes of Health Stroke Scale scores at admission to reconstruct previously published prehospital stroke scales. We compared the sensitivity of each scale for different occlusion locations. Occlusions were assessed with CT angiography by an imaging core laboratory blinded to clinical findings.

resultsWe included 3021 patients for the analysis of 14 scales. All scales had the highest sensitivity to detect internal carotid artery terminus occlusions (ranging from 0.21 to 0.97) and lowest for occlusions of the M2 segment (0.08 to 0.84, p-values < 0.001).

Indexed as

endovascular thrombectomyprehospital stroke scalesStroke

Identifiers

PMID34414295
PMCPMC8370085
OpenAlexW3160154260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.