Evidence map›Paper›PMID 34414285›Full record

ReviewEuropean stroke journal2021

Cerebrovascular disease in patients with cognitive impairment: A white paper from the ESO dementia committee - A practical point of view with suggestions for the management of cerebrovascular diseases in memory clinics.

Ana Verdelho, Geert Jan Biessels, Hugues Chabriat, Andreas Charidimou, Marco Duering, Olivier Godefroy, Leonardo Pantoni, Aleksandra Pavlovic, Joanna Wardlaw

Open access · bronzeAbstract readReview
In one paragraph

Review in European stroke journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Luigi Sacco Hospital VAS-COG stroke care pathway: A five-year experience.Cerebral circulation - cognition and behavior · 2024
    Article
  6. Review
  7. Diagnosing vascular cognitive impairment: Current challenges and future perspectives.International journal of stroke : official journal of the International Stroke Society · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 9 countries.

Ana VerdelhoDepartment of Neurosciences and Mental Health, CHLN-Hospital de Santa Maria, Instituto de Medicina Molecular - IMM e Instituto de Saude Ambiental-ISAMB, Faculdade de Medicina. University of Lisbon, Lisbon, Portugal.ORCID https://orcid.org/0000-0003-4945-4946
Geert Jan BiesselsDepartment of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.
Hugues ChabriatDepartment of Neurology, FHU NeuroVasc, Hôpital Lariboisiere, University of Paris and INSERM U1141, Paris, France.
Andreas CharidimouHemorrhagic Stroke Research Program, J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Marco DueringInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Germany.
Olivier GodefroyDepartments of Neurology, Amiens University Hospital, and Laboratory of Functional Neurosciences1,6 (UR UPJV 4559), Jules Verne Picardy University, Amiens, France.
Leonardo PantoniStroke and Dementia Lab, "Luigi Sacco" Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.ORCID https://orcid.org/0000-0001-7357-8530
Aleksandra PavlovicFaculty for Special Education and Rehabilitation, University of Belgrade, Belgrade, Serbia.
Joanna WardlawCentre for Clinical Brain Sciences, UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0002-9812-6642
Boston University · USInserm · FRLaboratoire de neurosciences fonctionnelles et pathologies · FRUK Dementia Research Institute · GBUniversity Medical Center Utrecht · NLUniversity of Basel · CHUniversity of Belgrade · RSUniversity of Lisbon · PTUniversity of Milan · IT

Funding

Medical Research Council MR/L023784/2
6 · The paper itself

Abstract

purposePractical suggestions on clinical decisions about vascular disease management in patients with cognitive impairment are proposed.

methodsThe document was produced by the Dementia Committee of the European Stroke Organisation (ESO) based on the evidence from the literature where available and on the clinical experience of the Committee members. This paper was endorsed by the ESO.

findingsVascular risk factors and cerebrovascular disease are frequent in patients with cognitive impairment. While acute stroke treatment has evolved substantially in last decades, evidence of management of cerebrovascular pathology beyond stroke in patients with cognitive impairment and dementia is quite limited. Additionally, trials to test some daily-life clinical decisions are likely to be complex, difficult to undertake and take many years to provide sufficient evidence to produce recommendations. This document was conceived to provide some suggestions until data from field trials are available. It was conceived for the use of clinicians from memory clinics or involved specifically in cognitive disorders, addressing practical aspects on diagnostic tools, vascular risk management and suggestions on some therapeutic options. DISCUSSION AND

conclusionsThe authors did not aim to do an exhaustive or systematic review or to cover all current evidence. The document approach in a very practical way frequent issues concerning cerebrovascular disease in patients with known cognitive impairment.

Indexed as

Cerebrovascular diseasecognitive impairmentdementiasmall vessel diseasestroke

Identifiers

PMID34414285
PMCPMC8370070
OpenAlexW3127683227

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.