Evidence map›Paper›PMID 34414202›Full record

ArticleFrontiers in medicine2021

Oral Scutellarin Treatment Ameliorates Retinal Thinning and Visual Deficits in Experimental Glaucoma.

Jingyuan Zhu, Anoop Sainulabdeen, Krystal Akers, Vishnu Adi, Jeffrey R Sims, Eva Yarsky, Yi Yan, Yu Yu, Hiroshi Ishikawa, Christopher K Leung and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Testing Visual Function by Assessment of the Optomotor Reflex in Glaucoma.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Ocular manifestations of central insulin resistance.Neural regeneration research · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 4 countries.

Jingyuan ZhuBeijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Anoop SainulabdeenDepartment of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, United States.
Krystal AkersDepartment of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, United States.
Vishnu AdiDepartment of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, United States.
Jeffrey R SimsDepartment of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, United States.
Eva YarskyDepartment of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, United States.
Yi YanDepartment of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, United States.
Yu YuPleryon Therapeutics Limited, Shenzhen, China.
Hiroshi IshikawaDepartment of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, United States.
Christopher K LeungHong Kong Eye Hospital, University Eye Center, Hong Kong, China.
Gadi WollsteinDepartment of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, United States.
Joel S SchumanDepartment of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, United States.
Wenbin WeiBeijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Kevin C ChanDepartment of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, United States.
New York University · USCapital Medical University · CNHong Kong Eye Hospital · CNKerala Veterinary and Animal Sciences University · IN

Funding

Novel Glaucoma Diagnostics for Structure and Function - Renewal - 1R01EY013178 · NEI · WILLS EYE HEALTH SYSTEM · PI Joel S Schuman · 2000 to 2026
$17.5M
Glaucoma Neuroimaging in Humans and Experimental Animal ModelsR01EY028125 · NEI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHAN, KEVIN C · 2017 to 2021
$2.2M
NEI NIH HHS R01 EY013178NEI NIH HHS R01 EY028125
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

glaucomaintraocular pressureoptokineticsretinascutellarin

Identifiers

PMID34414202
PMCPMC8369066
OpenAlexW3191054594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.