ArticleInternational journal of ophthalmology2021
Macular density alterations in myopic choroidal neovascularization and the effect of anti-VEGF on it.
Article in International journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Macular vessel density in patients with refractory diabetic macular edema in different stages of nonproliferative diabetic retinopathy.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025Article
- Perifoveal Exudative Vascular Anomalous Complex (PEVAC): Retinal Vascular Density Findings.Journal of clinical medicine · 2024Article
- Biomarker Signature in Aqueous Humor Mirrors Lens Epithelial Cell Activation: New Biomolecular Aspects from Cataractogenic Myopia.Biomolecules · 2023Article
- Evaluation of macular neovascularization activity in pathological myopia: a comparison between optical coherence tomography and OCT-angiography.Frontiers in medicine · 2023Article
- An ImageJ macro tool for OCTA-based quantitative analysis of Myopic Choroidal neovascularization.PloS one · 2023Article
- Different approaches for treating myopic choroidal neovascularization: a network Meta-analysis.International journal of ophthalmology · 2023Article
- Factors associated with the recurrence of choroidal neovascularization in pathologic myopia.Frontiers in medicine · 2022Article
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Authors and funding
10 authors.
Funding
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Abstract
aimTo analyse macular microvascular alterations in myopic choroidal neovascularization (mCNV) and the efficiency of anti-vascular endothelial growth factor (anti-VEGF) therapy for mCNV by optical coherence tomography angiography (OCTA).
methodsA total of 123 patients were included in this retrospective study, divided into mCNV group, high myopia (HM) group, and normal group at the Affiliated Eye Hospital of Wenzhou Medical University from January 2017 to January 2019. Superficial vessel density, deep capillary density, foveal avascular zone (FAZ) area, A-circularity index (AI) and vessel density around the 300 µm width of the FAZ region density (FD) and the area of choroidal neovascularization (CNV) lesion (only for mCNV group) were measured on 3×3 mm
resultsThere were significant differences among 3 groups in superficial vessel density, deep capillary density and FD (
conclusionMacular vessel density decreases, FAZ turns smaller and more irregular in mCNV eyes. Anti-VEGF therapy is efficient for mCNV without affecting vessel density and FAZ, but it is unable to completely eliminate CNV lesions in most cases. The bigger mCNV lesions have lower reduction ratio.
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