Evidence map›Paper›PMID 34413857›Full record

ArticleFrontiers in immunology2021

Granzyme A Produced by γ

Valerio Rasi, David C Wood, Christopher S Eickhoff, Mei Xia, Nicola Pozzi, Rachel L Edwards, Michael Walch, Niels Bovenschen, Daniel F Hoft

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Valerio RasiDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Saint Louis, MO, United States.
David C WoodDepartment of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, MO, United States.
Christopher S EickhoffDepartment of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO, United States.
Mei XiaDepartment of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO, United States.
Nicola PozziDepartment of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, MO, United States.
Rachel L EdwardsDepartment of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO, United States.
Michael WalchAnatomy Unit, Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.
Niels BovenschenDepartment of Pathology, University Medical Center Utrecht, Utrecht, Netherlands.
Daniel F HoftDepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Saint Louis, MO, United States.
Saint Louis University · USUniversity Medical Center Utrecht · NLUniversity of Fribourg · CH

Funding

Role of gammadelta T Cells in Vaccine-Induced ImmunityR01AI048391 · NIAID · SAINT LOUIS UNIVERSITY · PI HOFT, DANIEL F. · 2002 to 2019
$6.1M
Structural Studies of Beta-2 glycoprotein I in the Antiphospholipid SyndromeR01HL150146 · NHLBI · SAINT LOUIS UNIVERSITY · PI POZZI, NICOLA · 2020 to 2024
$2.0M
Mechanistic investigations of Granzyme A-mediated γ9δ2 T cell TB protective effectsF30HL151136 · NHLBI · SAINT LOUIS UNIVERSITY · PI RASI, VALERIO · 2020 to 2023
$162k
NHLBI NIH HHS F30 HL151136NHLBI NIH HHS R01 HL150146NIAID NIH HHS R01 AI048391
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenosine TriphosphateBlotting, WesternCell DivisionEndoplasmic Reticulum StressGranzymesHEK293 CellsHumansMemory T CellsMonocytesMycobacterium bovisProteomeReceptors, Antigen, T-Cell, gamma-deltaRecombinant ProteinsT-Lymphocyte SubsetsTwo-Dimensional Difference Gel ElectrophoresisAdenosine TriphosphateGranzymesGZMA protein, humanProteomeReceptors, Antigen, T-Cell, gamma-deltaRecombinant Proteins2D-DIGEATP productionBCGER stress responseGranzyme AGZMAhuman monocyteMycobacterium tuberculosis

Identifiers

PMID34413857
PMCPMC8368726
OpenAlexW3188480245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.