Evidence map›Paper›PMID 34413786›Full record

ArticleFrontiers in physiology2021

Blood Flow and Shear Stress Allow Monitoring of Progression and Prognosis of Tumor Diseases.

Matthias Barral, Imane El-Sanharawi, Anthony Dohan, Maxime Sebuhyan, Alexis Guedon, Audrey Delarue, Alexandre Boutigny, Nassim Mohamedi, Benjamin Magnan, Salim Kemel and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Matthias BarralINSERM UMR1275, Université de Paris, Hôpital Lariboisière, Paris, France.
Imane El-SanharawiAP-HP, Université de Paris, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Paris, France.
Anthony DohanINSERM UMR1275, Université de Paris, Hôpital Lariboisière, Paris, France.
Maxime SebuhyanAP-HP, Université de Paris, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Paris, France.
Alexis GuedonAP-HP, Université de Paris, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Paris, France.
Audrey DelarueAP-HP, Université de Paris, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Paris, France.
Alexandre BoutignyAP-HP, Université de Paris, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Paris, France.
Nassim MohamediAP-HP, Université de Paris, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Paris, France.
Benjamin MagnanAP-HP, Université de Paris, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Paris, France.
Salim KemelAP-HP, Université de Paris, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Paris, France.
Chahinez KetfiAP-HP, Université de Paris, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Paris, France.
Nathalie KubisAP-HP, Université de Paris, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Paris, France.
Annouk Bisdorff-BressonAP-HP, Université de Paris, Hôpital Lariboisière, Neuroradiologie, Centre Constitutif des Malformations Artério Veineuses Superficielles de l'Enfant et de l'Adulte, Paris, France.
Marc PocardINSERM UMR1275, Université de Paris, Hôpital Lariboisière, Paris, France.
Philippe BonninAP-HP, Université de Paris, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Paris, France.
Hôpital Lariboisière · FRUniversité Paris Cité · FRAssistance Publique – Hôpitaux de Paris · FRInserm · FRLaboratoire de Recherche Vasculaire Translationnelle · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the presence of tumor angiogenesis, blood flow must increase, leading to an elevation of blood flow velocities (BFVels) and wall shear stress (WSS) in upstream native arteries. An adaptive arterial remodeling is stimulated, whose purpose lies in the enlargement of the arterial inner diameter, aiming for normalization of BFVels and WSS. Remodeling engages delayed processes that are efficient only several weeks/months after initiation, independent from those governing expansion of the neovascular network. Therefore, during tumor expansion, there is a time interval during which elevation of BFVels and WSS could reflect disease progression. Conversely, during the period of stability, BFVels and WSS drop back to normal values due to the achievement of remodeling processes. Ovarian peritoneal carcinomatosis (OPC), pseudomyxoma peritonei (PMP), and superficial arteriovenous malformations (AVMs) are diseases characterized by the development of abnormal vascular networks developed on native ones. In OPC and PMP, preoperative blood flow in the superior mesenteric artery (SMA) correlated with the per-operative peritoneal carcinomatosis index (OPC:

Indexed as

arteriovenous malformationblood flow velocitycarotid arterydisease progressionperitoneal carcinomatosispseudomyxoma peritoneisuperior mesenteric arterywall shear stress

Identifiers

PMID34413786
PMCPMC8369886
OpenAlexW3189696284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.