Evidence map›Paper›PMID 34413685›Full record

ArticleInternational medical case reports journal2021

Multiple Sclerosis Presenting with Sixth Nerve Palsy in a Child.

Nada Al-Yousuf, Lolwah Aljutaili, Aisha AlHuwais, Abdullah Almutairi, Hasan Alsetri, Moiz Bakhiet

Open access · goldAbstract readCase Reports
In one paragraph

Article in International medical case reports journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Nada Al-YousufDepartment of Ophthalmology, King Abdullah Medical City, Manama, Kingdom of Bahrain.
Lolwah AljutailiCollege of Medicine & Medical Sciences, Arabian Gulf University, Manama, Kingdom of Bahrain.
Aisha AlHuwaisCollege of Medicine & Medical Sciences, Arabian Gulf University, Manama, Kingdom of Bahrain.
Abdullah AlmutairiCollege of Medicine & Medical Sciences, Arabian Gulf University, Manama, Kingdom of Bahrain.
Hasan AlsetriDepartment of Chemistry & Biochemistry, University of California Los Angeles, Los Angeles, CA, USA.
Moiz BakhietDepartment of Molecular Medicine, College of Medicine & Medical Sciences, Arabian Gulf University, Manama, Kingdom of Bahrain.ORCID 0000-0002-5148-8849
Arabian Gulf University · BHUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a child with multiple sclerosis who presented with sixth nerve palsy. She is a twelve-year-old Bahraini female presented to the ophthalmology department complaining of double vision. She also had imbalance and paraesthesia. Extraocular muscle examination showed restriction of abduction in the right eye. There was no change in vision. MRI showed right eye optic neuritis (ON) and demyelination which was indicative of multiple sclerosis (MS). Ocular coherence tomography (OCT) showed thinning of nerve fibres of both eyes which was consistent with subclinical optic neuritis. Neurological examination showed brisk knee jerk on the left side and incoordination of movement on the same side. Disability Status Scale (EDSS) showed a score of 3.0. She was given Solu-medrol 500 mg intravenously (IV) in addition to omeprazole 40 mg IV and Vitamin D3 (cholecalciferol) 50,000 IU cap weekly for 8 weeks and Neurorubine forte tablets (vitamin B1, 6, 12) once a day for 2 months. She became asymptomatic in her follow-up visits. Children with MS can present as sixth cranial nerve palsy. Clinicians should have a high index of suspicion for early diagnosis and treatment. In addition to MRI, OCT is a useful diagnostic tool for optic neuritis and MS especially in children.

Indexed as

demyelinationdiplopialateral rectus palsyocular coherence tomography

Identifiers

PMID34413685
PMCPMC8370490
OpenAlexW3189463110

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.