ArticleScientific reports2021
Acircularity and circularity indexes of the foveal avascular zone in high myopia.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Alterations in macular microvasculature in chronic hepatitis B patients measured by optical coherence tomography angiography.Quantitative imaging in medicine and surgery · 2026Article
- Early Retinal Changes Detected Using Optical Coherence Tomography Angiography in Youth with Type 1 Diabetes Mellitus: A Case-Control Study.Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde · 2026Article
- Retinal and Choroidal Microvasculature at Different Myopia Severities: A Systematic Review and Meta-Analysis.Ophthalmology science · 2026Review
- Associations between axial length and optical coherence tomography angiography biomarkers.International journal of retina and vitreous · 2025Article
- Quantitative analysis of macular and optic disc microvascular parameters in patients with immunoglobulin A nephropathy using optical coherence tomography angiography.Quantitative imaging in medicine and surgery · 2025Article
- Association of Retinal Microvasculature With Myopia Progression in Children: The Hong Kong Children Eye Study.Investigative ophthalmology & visual science · 2025Article
- Automated Foveal Avascular Zone Segmentation in Optical Coherence Tomography Angiography Across Multiple Eye Diseases Using Knowledge Distillation.Bioengineering (Basel, Switzerland) · 2025Article
- Analysis of the correlations between changes in posterior segment and anterior chamber segment after implantable collamer lens implantation in highly myopic patients.BMC ophthalmology · 2025Observational
- Differences in macular structure and microvasculature between high myopia and non-high myopia.Frontiers in medicine · 2025Article
- OCTA-based evaluation of the correlation between macular retinal and choroidal structural characteristics and refractive status in patients with retinopathy of prematurity.Frontiers in pediatrics · 2025Article
- Evaluation of retinal and choroidal microvascular alteration after ICL V4c implantation based on OCTA.BMC ophthalmology · 2024Article
- Analysis of retinal and choroidal microvascular changes using optical coherence tomography and optical coherence tomography angiography in patients with acute leukemia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Severity Stratification of Coronary Artery Disease Using Novel Inner Ellipse-Based Foveal Avascular Zone Biomarkers.Investigative ophthalmology & visual science · 2024Article
- The Framework of Quantifying Biomarkers of OCT and OCTA Images in Retinal Diseases.Sensors (Basel, Switzerland) · 2024Article
- Applications of optical coherence tomography angiography in glaucoma: current status and future directions.Frontiers in medicine · 2024Review
- Macular Imaging Characteristics in Children with Myelinated Retinal Nerve Fiber and High Myopia Syndrome.Turkish journal of ophthalmology · 2023Article
- The Influence of Myopia on the Foveal Avascular Zone and Density of Blood Vessels of the Macula-An OCTA Study.Medicina (Kaunas, Lithuania) · 2023Article
- Enhanced Apoptosis in Choroidal Tissues in Lens-Induced Myopia Guinea Pigs by Activating the RASA1 Signaling Pathway.Investigative ophthalmology & visual science · 2022Article
- Various configuration types of the foveal avascular zone with related factors in normal Chinese adults with or without myopia assessed by swept-source OCT angiography.International journal of ophthalmology · 2022Article
- Effect of macular vascular density on visual quality in young myopic adults.Frontiers in medicine · 2022Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study explored the association between foveal avascular zone (FAZ) parameters and high myopia using optical coherence tomography angiography. We divided 106 eyes of 106 patients into quartiles based on the axial length. The upper quartile was then defined as the high myopia group (n = 27), while the lower quartile was the non-high myopia group (n = 26). The areas and minor axis lengths of superficial and deep FAZ, the perimeters and major axis lengths of deep FAZ were significantly larger in eyes with high myopia than in eyes with non-high myopia (P < 0.05). Inversely, the subfoveal choroidal thickness was significantly thinner in eyes with high myopia than in those with non-high myopia. Linear regression analyses showed that no significant correlation was observed between FAZ areas and acircularity and circularity indexes of FAZ in non-high myopia group. Conversely, FAZ areas strongly correlated with acircularity and circularity indexes of FAZ in high myopia group. We found that an increase in the FAZ area in highly myopic eyes was accompanied by a significant variation in FAZ acircularity and circularity indexes. Further research should address whether these findings are associated with future disease development in highly myopic eyes.
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