Evidence map›Paper›PMID 34413204›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Identification of Pattern Completion Neurons in Neuronal Ensembles Using Probabilistic Graphical Models.

Luis Carrillo-Reid, Shuting Han, Darik O'Neil, Ekaterina Taralova, Tony Jebara, Rafael Yuste

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

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  12. From calcium imaging to graph topology.Network neuroscience (Cambridge, Mass.) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Luis Carrillo-ReidDepartments of Biological Sciences and carrillo.reid@comunidad.unam.mx.ORCID 0000-0002-0511-2533
Shuting HanDepartments of Biological Sciences and.
Darik O'NeilDepartments of Biological Sciences and.ORCID 0000-0002-8222-7617
Ekaterina TaralovaDepartments of Biological Sciences and.
Tony JebaraComputer Science, Columbia University, New York, New York 10027.
Rafael YusteDepartments of Biological Sciences and.ORCID 0000-0003-4206-497X
Columbia University · USUniversidad del Caribe (UNICARIBE) · DO

Funding

IMAGING FUNCTIONAL CONNECTIVITY IN VISUAL CORTEXR01EY011787 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 1998 to 2021
$6.4M
Effect of GABAergic inhibition of dendritic spines on synaptic pruning in the medial prefrontal cortex during adolescenceR01MH115900 · NIMH · SUNY DOWNSTATE MEDICAL CENTER · PI SMITH, SHERYL S · 2019 to 2023
$3.2M
CRCNS: Modeling the nanophysiology of dendritic spinesR01NS110422 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 2018 to 2020
$744k
Optical methods for imaging and manipulating dendritic spines in vivoR34NS116740 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI ETCHENIQUE, ROBERTO, YUSTE, RAFAEL · 2020 to 2020
$700k
NEI NIH HHS R01 EY011787NIMH NIH HHS R01 MH115900NINDS NIH HHS R01 NS110422NINDS NIH HHS R34 NS116740
6 · The paper itself

Abstract

Neuronal ensembles are groups of neurons with coordinated activity that could represent sensory, motor, or cognitive states. The study of how neuronal ensembles are built, recalled, and involved in the guiding of complex behaviors has been limited by the lack of experimental and analytical tools to reliably identify and manipulate neurons that have the ability to activate entire ensembles. Such pattern completion neurons have also been proposed as key elements of artificial and biological neural networks. Indeed, the relevance of pattern completion neurons is highlighted by growing evidence that targeting them can activate neuronal ensembles and trigger behavior. As a method to reliably detect pattern completion neurons, we use conditional random fields (CRFs), a type of probabilistic graphical model. We apply CRFs to identify pattern completion neurons in ensembles in experiments using

Indexed as

Models, NeurologicalProbabilityAnimalsMaleMiceMice, Inbred C57BLMicroscopy, Fluorescence, MultiphotonNeuronsOptogeneticsPattern Recognition, VisualPhotic StimulationVisual CortexConditional random fieldsgraph theoryneuronal ensemblespattern completionprobabilistic graphical modelstwo-photon optogenetics

Identifiers

PMID34413204
PMCPMC8513696
OpenAlexW3195873474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.