Evidence map›Paper›PMID 34413138›Full record

ArticleGenes & development2021

Structural basis of PETISCO complex assembly during piRNA biogenesis in

Cecilia Perez-Borrajero, Nadezda Podvalnaya, Kay Holleis, Raffael Lichtenberger, Emil Karaulanov, Bernd Simon, Jérôme Basquin, Janosch Hennig, René F Ketting, Sebastian Falk

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Cecilia Perez-BorrajeroStructural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL) Heidelberg, 69117 Heidelberg, Germany.ORCID 0000-0002-3167-7159
Nadezda Podvalnaya *Biology of Noncoding RNA Group, Institute of Molecular Biology, 55128 Mainz, Germany.
Kay Holleis *Department of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, 1030 Vienna, Austria.
Raffael LichtenbergerDepartment of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, 1030 Vienna, Austria.
Emil KaraulanovBioinformatics Core Facility, Institute of Molecular Biology, 55099 Mainz, Germany.
Bernd SimonStructural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL) Heidelberg, 69117 Heidelberg, Germany.ORCID 0000-0003-0164-5516
Jérôme BasquinDepartment of Structural Cell Biology, Max-Planck-Institute of Biochemistry, 82152 Martinsried, Germany.ORCID 0000-0003-2151-3991
Janosch HennigStructural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL) Heidelberg, 69117 Heidelberg, Germany.ORCID 0000-0001-5214-7002
René F KettingBiology of Noncoding RNA Group, Institute of Molecular Biology, 55128 Mainz, Germany.ORCID 0000-0001-6161-5621
Sebastian FalkDepartment of Structural and Computational Biology, Max Perutz Laboratories, University of Vienna, 1030 Vienna, Austria.ORCID 0000-0001-7848-4621
European Molecular Biology Laboratory · DEUniversity of Vienna · ATGene Therapy Laboratory · FRInstitute of Molecular Biology · DEJohannes Gutenberg University Mainz · DEMax Planck Institute of Biochemistry · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Piwi-interacting RNAs (piRNAs) constitute a class of small RNAs that bind PIWI proteins and are essential to repress transposable elements in the animal germline, thereby promoting genome stability and maintaining fertility.

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsArgonaute ProteinsDNA Transposable ElementsGerm CellsRNA, Small InterferingArgonaute ProteinsCaenorhabditis elegans ProteinsDNA Transposable ElementsRNA, Small Interfering21U RNAC. elegansERH-2IFE-3PETISCOPID-1PID-3piRNAPiwiRRM domainTOFU-6TOST-1

Identifiers

PMID34413138
PMCPMC8415317
OpenAlexW3194405129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.