Evidence map›Paper›PMID 34413068›Full record

ArticleDiabetes care2021

Incidence of Type 1 Diabetes May Be Underestimated in the Chinese Population: Evidence From 21.7 Million People Between 2007 and 2017.

Chang Liu, Ying-Chao Yuan, Mo-Ning Guo, Zhong Xin, Guan-Jie Chen, Amy R Bentley, Lin Hua, Jian-Peng Zheng, Kenneth Ekoru, Jin-Kui Yang

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 48 citations in OpenAlex.

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  6. [Research progress and optimization strategies for early screening of type 1 diabetes].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
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  16. Neutrophil extracellular traps in homeostasis and disease.Signal transduction and targeted therapy · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Chang LiuDepartment of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Ying-Chao YuanDepartment of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Mo-Ning GuoBeijing Municipal Health Commission Information Center, Beijing, China.
Zhong XinDepartment of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Guan-Jie ChenThe Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD.
Amy R BentleyThe Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD.
Lin HuaSchool of Biomedical Engineering, Capital Medical University, Beijing, China.
Jian-Peng ZhengBeijing Municipal Health Commission Information Center, Beijing, China.
Kenneth EkoruThe Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD.
Jin-Kui YangDepartment of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China jkyang@ccmu.edu.cn.ORCID 0000-0002-5430-2149
Beijing Tongren Hospital · CNNational Institutes of Health · USBeijing Municipal Education Commission · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePrevious reports of the annual incidence of type 1 diabetes (T1D) in China were conducted using retrospective hospital cases, which may not reflect the reality. This longitudinal study estimated T1D incidence in a Chinese population of 21.7 million from 2007 to 2017. RESEARCH DESIGN AND

methodsA population-based registry of T1D was performed by the Beijing Municipal Health Commission Information Center. Annual incidence and 95% CIs were calculated by age group and sex. The association of sex with T1D incidence and predicted new cases of T1D were assessed using Poisson regression models. Annual percentage change and average annual percentage of change were assessed using Joinpoint regression.

resultsOverall, there were 6,875 individuals who developed T1D from 2007 to 2017 in this population. T1D incidence (/100,000 persons) (95% CI) significantly increased from 2.72 (2.51, 2.93) in 2007 to 3.60 (3.38, 3.78) in 2017 (

conclusionsT1D incidence in this large Chinese population is higher than has been reported previously. From 2007 to 2017, although the incidence peak was in the 10-14-year age group, the T1D incidence increased sharply in adults but not in youth.

Indexed as

Diabetes Mellitus, Type 1AdolescentAdultChildChild, PreschoolChinaFemaleHumansIncidenceInfantInfant, NewbornLongitudinal StudiesMaleRetrospective StudiesYoung Adult

Identifiers

PMID34413068
PMCPMC8546282
OpenAlexW3194518908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.