Evidence map›Paper›PMID 34413035›Full record

ArticleBMJ case reports2021

Clinical efficacy with dabrafenib and trametinib in a T599_V600insT poorly differentiated metastatic thyroid carcinoma.

Chung-Shien Lee, Emily Miao, Kasturi Das, Nagashree Seetharamu

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Chung-Shien LeeDivision of Medical Oncology and Hematology, Northwell Health Cancer Institute, Lake Success, New York, USA leec3@stjohns.edu.ORCID http://orcid.org/0000-0003-3505-6402
Emily MiaoPharmacy Department, North Shore University Hospital, Manhasset, New York, USA.
Kasturi DasDivision of Cytopathology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Greenvale, New York, USA.
Nagashree SeetharamuDivision of Medical Oncology and Hematology, Northwell Health Cancer Institute, Lake Success, New York, USA.ORCID http://orcid.org/0000-0002-3282-7622
Northwell Health · USDonald & Barbara Zucker School of Medicine at Hofstra/Northwell · USNorth Shore University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BRAF (v-raf murine sarcoma viral oncogene homolog B1) and MEK (mitogen-activated protein kinase kinase) inhibitors have been shown to improve clinical outcomes in tumours presenting with mutations in the

Indexed as

OximesThyroid NeoplasmsAnimalsHumansImidazolesMicePyridonesPyrimidinonesTreatment OutcomedabrafenibImidazolesOximesPyridonesPyrimidinonestrametinibcancer interventiononcologytyrosine kinase inhibitor

Identifiers

PMID34413035
PMCPMC8378374
OpenAlexW3195081105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.