Evidence map›Paper›PMID 34413031›Full record

ArticleBMJ case reports2021

Bullous fixed drug eruption following administration of the recombinant adjuvant Shingrix vaccine.

Hallie Thompson, Laura Nichols, Tania Gonzalez Santiago

Open access · hybridAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Skin manifestations after immunisation with an adjuvanted recombinant zoster vaccine, Germany, 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  3. Article
  4. Dermatomal rash after Shingrix vaccination: cause or coincidence?Proceedings (Baylor University. Medical Center) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hallie ThompsonUniversity of North Dakota, Edgeley, North Dakota, USA hallie.b.anderson@und.edu.
Laura NicholsSanford Health North, Fargo, North Dakota, USA.
Tania Gonzalez SantiagoSanford Health North, Fargo, North Dakota, USA.
Sanford Health · USUniversity of North Dakota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 51-year-old woman with Crohn's disease presented with a bullous rash on her left arm and axilla 2 days after receiving her second dose of the recombinant adjuvant Shingrix vaccine. PCR for herpes simplex virus (HSV) 1, HSV 2 and varicella zoster virus was negative. Punch biopsy revealed changes that were consistent with a bullous fixed drug eruption. She was successfully treated oral prednisone and topical triamcinolone cream. This is the first known case of a bullous fixed drug eruption due to the recombinant adjuvant Shingrix vaccine.

Indexed as

Drug EruptionsHerpes ZosterVaccinesAdjuvants, ImmunologicFemaleHerpesvirus 3, HumanHumansMiddle AgedAdjuvants, ImmunologicVaccinesdermatologygeneral practice / family medicineimmunological products and vaccinesskinunwanted effects / adverse reactions

Identifiers

PMID34413031
PMCPMC8378370
OpenAlexW3194164411

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.