Evidence map›Paper›PMID 34412565›Full record

ArticleCell cycle (Georgetown, Tex.)2021

CHSY1 is upregulated and acts as tumor promotor in gastric cancer through regulating cell proliferation, apoptosis, and migration.

Jingjing Liu, Zhenwei Tian, Tianzhou Liu, Dacheng Wen, Zhiming Ma, Yuanda Liu, Jiaming Zhu

Open access · bronzeAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jingjing LiuDepartment of Gastrointestinal Surgery, The Second Hospital of Jilin University, Changchun, Jilin, China.
Zhenwei TianIntensive Care Unit, the Second Hospital of Jilin University, Changchun, Jilin, China.
Tianzhou LiuDepartment of Gastrointestinal Surgery, The Second Hospital of Jilin University, Changchun, Jilin, China.
Dacheng WenDepartment of Gastrointestinal Surgery, The Second Hospital of Jilin University, Changchun, Jilin, China.
Zhiming MaDepartment of Gastrointestinal Surgery, The Second Hospital of Jilin University, Changchun, Jilin, China.
Yuanda LiuDepartment of Gastrointestinal Surgery, The Second Hospital of Jilin University, Changchun, Jilin, China.
Jiaming ZhuDepartment of Gastrointestinal Surgery, The Second Hospital of Jilin University, Changchun, Jilin, China.
Second Affiliated Hospital of Jilin University · CNChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer is one of the most frequently diagnosed malignant tumors, with rapid progression and poor prognosis. The role of chondroitin sulfate synthase 1 (CHSY1) in the development and progression of gastric cancer was explored and clarified in this study. The immunohistochemistry analysis of clinical tissue samples as well as data mining of public database showed that CHSY1 was significantly upregulated in gastric cancer and associated with more advanced tumor stage and poorer prognosis.

Indexed as

AgedAnimalsApoptosisCarcinogenesisCell Line, TumorCell MovementCell ProliferationFemaleGene Expression Regulation, NeoplasticGene Knockdown TechniquesGlucuronosyltransferaseHumansMiceMice, Inbred BALB CMice, NudeMiddle AgedCHSY1 protein, humanGlucuronosyltransferaseMultifunctional EnzymesN-Acetylgalactosaminyltransferasescell apoptosiscell migrationcell proliferationCHSY1Gastric cancer

Identifiers

PMID34412565
PMCPMC8525991
OpenAlexW3195759016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.