ArticlePhysics in medicine and biology2021
TOPAS-nBio validation for simulating water radiolysis and DNA damage under low-LET irradiation.
Article in Physics in medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- TOPAS-nBio simulation of the impact of ultrahigh dose rate and oxygen concentration on the Fenton reaction using the Fricke solution.Medical physics · 2026Article
- A closed‑form reaction‑kinetics model for LET‑ and oxygen‑dependent hydroxyl radical availability under irradiation.Scientific reports · 2026Article
- Ultra-high dose rate dependent modeling of plasmid DNA damage with TOPAS-nBio.Physics in medicine and biology · 2026Article
- Electron transport (0.2 eV-10 keV) in liquid water: resolving discrepancies between track simulations and radiolysis data.RSC advances · 2026Article
- Extending the microdosimetry gamma model (MGM) to estimate induced DNA damage and its complexity at macroscopic scale by protons and helium ions.Physics in medicine and biology · 2025Article
- The role of coating layers in gold nanorods' radioenhancement: a Monte Carlo analysis.Nanoscale advances · 2025Article
- TOPAS-nBio-Reg: a regression testing system for track structure simulations in TOPAS-nBio.Physics in medicine and biology · 2025Article
- Effect of FLASH dose-rate and oxygen concentration in the production of HPhysics in medicine and biology · 2025Article
- Investigation of hydrogen peroxide yields and oxygen consumption in high dose rate irradiation: a TOPAS-nBio Monte Carlo study.Physics in medicine and biology · 2024Article
- Modeling the oxygen effect in DNA strand break induced by gamma-rays with TOPAS-nBio.Physics in medicine and biology · 2024Article
- A clustering tool for generating biological geometries for computational modeling in radiobiology.Physics in medicine and biology · 2024Article
- Review of chemical models and applications in Geant4-DNA: Report from the ESA BioRad III Project.Medical physics · 2024Review
- Lithium inelastic cross-sections and their impact on micro and nano dosimetry of boron neutron capture.Physics in medicine and biology · 2024Article
- Estimation of relative biological effectiveness ofEJNMMI physics · 2023Article
- GEANT4-DNA simulation of temperature-dependent and pH-dependent yields of chemical radiolytic species.Physics in medicine and biology · 2023Article
- An integrated Monte Carlo track-structure simulation framework for modeling inter and intra-track effects on homogenous chemistry.Physics in medicine and biology · 2023Article
- The complexity of DNA damage by radiation follows a Gamma distribution: insights from the Microdosimetric Gamma Model.Frontiers in oncology · 2023Article
- Modeling of DNA Damage Repair and Cell Response in Relation to p53 System Exposed to Ionizing Radiation.International journal of molecular sciences · 2022Article
- Impact of DNA Geometry and Scoring on Monte Carlo Track-Structure Simulations of Initial Radiation-Induced Damage.Radiation research · 2022Article
- TOPAS-nBio simulation of temperature-dependent indirect DNA strand break yields.Physics in medicine and biology · 2022Article
Corrections and comments
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Authors and funding
15 authors at 10 institutions in 5 countries.
Funding
Abstract
The chemical stage of the Monte Carlo track-structure simulation code Geant4-DNA has been revised and validated. The root-mean-square (RMS) empirical parameter that dictates the displacement of water molecules after an ionization and excitation event in Geant4-DNA has been shortened to better fit experimental data. The pre-defined dissociation channels and branching ratios were not modified, but the reaction rate coefficients for simulating the chemical stage of water radiolysis were updated. The evaluation of Geant4-DNA was accomplished with TOPAS-nBio. For that, we compared predicted time-dependent
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.