ArticleDevelopmental cognitive neuroscience2021
Neighborhood disadvantage and longitudinal brain-predicted-age trajectory during adolescence.
Article in Developmental cognitive neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Annual Research Review: Associations of socioeconomic status with cognitive function, language ability, and academic achievement in youth: a systematic review of mechanisms and protective factors.Journal of child psychology and psychiatry, and allied disciplines · 2025Pooled it
- BrainAGE, brain health, and mental disorders: A systematic review.Neuroscience and biobehavioral reviews · 2024Pooled it
- Sleep and participation in extracurricular activities moderate associations between low SES and brain structure and functional connectivity.Developmental cognitive neuroscience · 2026Article
- White matter reflects the childhood exposome.bioRxiv : the preprint server for biology · 2026Article
- Individual differences in adolescent cortical development are associated with neighborhood characteristics: Longitudinal findings from the ABCD study.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Perceived Racism, Brain Development, and Internalizing and Externalizing Symptoms: Findings From the ABCD Study.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Article
- Childhood Opportunity Index 2.0 and Cognition via the NIH Toolbox.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026Article
- Geographic Measures of Early Life-Course Social Exposome in the Evaluation of Structural Neuroanatomy: A Scoping Review.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Review
- A Systematic Evaluation of the Performance of Multiple Brain Age Algorithms in Two Cohorts of Youth.Human brain mapping · 2026Article
- Brain Age in Conduct Disorder:: A Mega-Analysis of the ENIGMA Antisocial Behavior Working Group.bioRxiv : the preprint server for biology · 2026Article
- Social Determinants of Health, the developing brain, and risk and resilience for psychopathology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- The Role of Neighborhood and Parenting in the Development of Effortful Control During Early Childhood.Child & youth care forum · 2026Article
- Current challenges and future directions for brain age prediction in children and adolescents.Nature communications · 2025Review
- Fine particulate matter air pollution and longitudinal gray matter development changes during early adolescence: variation by neighborhood disadvantage level.Environment international · 2025Article
- The effects of adverse life events on brain development in the ABCD study®: a propensity-weighted analysis.Molecular psychiatry · 2025Article
- The role of socioeconomic status in shaping associations between sensory association cortex and prefrontal structure and implications for executive function.Developmental cognitive neuroscience · 2025Article
- Assessing neurocognitive maturation in early adolescence based on baby and adult functional brain landscapes.Developmental cognitive neuroscience · 2025Article
- The Childhood Opportunity Index 2.0: Factor Structure in 9-10 Year Olds in the Adolescent Brain Cognitive Development Study.International journal of environmental research and public health · 2025Article
- Investigating cross-sectional and longitudinal relationships between brain structure and distinct dimensions of externalizing psychopathology in the ABCD sample.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- The association between neighborhood environment, prenatal exposure to alcohol and tobacco, and structural brain development.Frontiers in human neuroscience · 2025Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Neighborhood disadvantage has consistently been linked to alterations in brain structure; however, positive environmental (e.g., positive parenting) and psychological factors (e.g., temperament) may buffer these effects. We aimed to investigate associations between neighborhood disadvantage and deviations from typical neurodevelopmental trajectories during adolescence, and examine the moderating role of positive parenting and temperamental effortful control (EC). Using a large dataset (n = 1313), a normative model of brain morphology was established, which was then used to predict the age of youth from a longitudinal dataset (n = 166, three time-points at age 12, 16, and 19). Using linear mixed models, we investigated whether trajectories of the difference between brain-predicted-age and chronological age (brainAGE) were associated with neighborhood disadvantage, and whether positive parenting (positive behavior during a problem-solving task) and EC moderated these associations. We found that neighborhood disadvantage was associated with positive brainAGE during early adolescence and a deceleration (decreasing brainAGE) thereafter. EC moderated this association such that in disadvantaged adolescents, low EC was associated with delayed development (negative brainAGE) during late adolescence. Findings provide evidence for complex associations between environmental and psychological factors, and brain maturation. They suggest that neighborhood disadvantage may have long-term effects on neurodevelopment during adolescence, but high EC could buffer these effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.