Evidence map›Paper›PMID 34411765›Full record

ArticleAcademic pediatrics

Trends in Pediatric Viral Symptoms, Influenza Testing, and SARS-CoV-2 Testing From a Statewide Electronic Health Record Consortium, January 2017 to July 2021.

Rohan Khazanchi, Alicen B Spaulding, Peter J Bodurtha, Claire Neely, Tyler N A Winkelman, Minnesota EHR Consortium

Abstract read
In one paragraph

Article in Academic pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rohan KhazanchiHealth, Homelessness, and Criminal Justice Lab, Hennepin Healthcare Research Institute (R Khazanchi, PJ Bodurtha, TNA Winkelman), Minneapolis, Minn; School of Public Health, University of Minnesota (R Khazanchi), Minneapolis, Minn; College of Medicine, University of Nebraska Medical Center (R Khazanchi), Omaha, Nebr.
Alicen B SpauldingChildren's Minnesota Research Institute (AB Spaulding), Minneapolis, Minn.
Peter J BodurthaHealth, Homelessness, and Criminal Justice Lab, Hennepin Healthcare Research Institute (R Khazanchi, PJ Bodurtha, TNA Winkelman), Minneapolis, Minn.
Claire NeelyInstitute for Clinical Systems Improvement (C Neely), Minneapolis, Minn.
Tyler N A WinkelmanHealth, Homelessness, and Criminal Justice Lab, Hennepin Healthcare Research Institute (R Khazanchi, PJ Bodurtha, TNA Winkelman), Minneapolis, Minn; Division of General Internal Medicine, Department of Medicine, Hennepin Healthcare (TNA Winkelman), Minneapolis, Minn. Electronic address: tyler.winkelman@hcmed.org.
Minnesota EHR Consortium

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
NCATS NIH HHS UL1 TR002494
6 · The paper itself

Abstract

objectiveThe heterogeneous implementation and uptake of nonpharmaceutical interventions (NPIs) during the coronavirus disease 2019 (COVID-19) pandemic amplified the need for locally responsive disease surveillance mechanisms. Using data from a newly developed statewide electronic health record (EHR) consortium in Minnesota, we sought to characterize trends in pediatric viral symptoms, influenza testing, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing.

methodsWe conducted a serial cross-sectional analysis of EHR data from 1/1/2017 to 7/30/2021 across 8 large health systems in Minnesota. We included patients ≤18 years of age with any SARS-CoV-2 test, influenza test, or documented diagnostic code which met our viral symptom definition. We plotted week-by-week trends in viral symptoms, SARS-CoV-2 and influenza testing, and test positivity, stratified between children (0-11 years) and adolescents (12-18 years).

resultsWe identified 1,079,924 patients ≤18 years of age with viral symptoms or testing; 880,669 (81.5%) were children ≤11 years. Influenza testing and influenza test positivity remained well below historical averages from March 2020 through mid-May 2021. Peaks in viral symptoms during this time were concomitant with peaks in SARS-CoV-2 testing and test positivity, whereas influenza testing and test positivity remained stagnant. Influenza test positivity rates increased substantively among children from May through July 2021.

conclusionsViral illness and influenza testing among pediatric patients were below historical averages throughout the COVID-19 pandemic. Ongoing increases in influenza test positivity may merit clinical and public health awareness and intervention. Future NPI policies can be better targeted with insights from collaborative EHR-based surveillance, which enhances real-time, locally sensitive measurement of disease outbreaks.

Indexed as

COVID-19Influenza, HumanAdolescentChildCOVID-19 TestingCross-Sectional StudiesElectronic Health RecordsHumansPandemicsSARS-CoV-2coronavirus disease 2019electronic health recordhealth informaticsinfluenzapublic healthsystemic acute respiratory syndrome coronavirus 2viral surveillance

Identifiers

PMID34411765
PMCPMC8415763

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.