Evidence map›Paper›PMID 34411538›Full record

ArticleAmerican journal of human genetics2021

Patterns of genetic connectedness between modern and medieval Estonian genomes reveal the origins of a major ancestry component of the Finnish population.

Toomas Kivisild, Lehti Saag, Ruoyun Hui, Simone Andrea Biagini, Vasili Pankratov, Eugenia D'Atanasio, Luca Pagani, Lauri Saag, Siiri Rootsi, Reedik Mägi and 12 more

Abstract readHistorical Article
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of human genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  10. Capturing the fusion of two ancestries and kinship structures in Merovingian Flanders.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Toomas KivisildDepartment of Human Genetics, KU Leuven, Leuven 3000, Belgium; Estonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia; McDonald Institute for Archaeological Research, University of Cambridge, Cambridge CB2 3ER, UK. Electronic address: toomas.kivisild@kuleuven.be.
Lehti SaagEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia; Research Department of Genetics, Evolution, and Environment, University College London, London WC1E 6BT, UK.
Ruoyun HuiMcDonald Institute for Archaeological Research, University of Cambridge, Cambridge CB2 3ER, UK; The Alan Turing Institute, British Library, 96 Euston Road, London NW1 2DB, UK.
Simone Andrea BiaginiDepartment of Human Genetics, KU Leuven, Leuven 3000, Belgium.
Vasili PankratovEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.
Eugenia D'AtanasioInstituto di Biologia e Patologia Molecolari, Consiglio Nazionale delle Ricerche, Rome, Italy.
Luca PaganiEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia; Department of Biology, University of Padova, 35131 Padova, Italy.
Lauri SaagEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.
Siiri RootsiEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.
Reedik MägiEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.
Ene MetspaluEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.
Heiki ValkDepartment of Archaeology, Institute of History and Archaeology, University of Tartu, Tartu 51014, Estonia.
Martin MalveDepartment of Archaeology, Institute of History and Archaeology, University of Tartu, Tartu 51014, Estonia.
Kadri IrdtEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.
Tuuli ReisbergCore Facility, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.
Anu SolnikCore Facility, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.
Christiana L ScheibEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia; McDonald Institute for Archaeological Research, University of Cambridge, Cambridge CB2 3ER, UK; St John's College, University of Cambridge, Cambridge CB2 1TP, UK.
Daniel N SeidmanDepartment of Computational Biology, Cornell University, Ithaca, NY 14853, USA.
Amy L WilliamsDepartment of Computational Biology, Cornell University, Ithaca, NY 14853, USA.
Estonian Biobank Research TeamEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.
Kristiina TambetsEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.
Mait MetspaluEstonian Biocentre, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.

Funding

Scalable methods for the characterization and analysis of families in large genomic datasetsR35GM133805 · NIGMS · CORNELL UNIVERSITY · PI WILLIAMS, AMY LYNNE · 2019 to 2023
$1.6M
NIGMS NIH HHS R35 GM133805Wellcome Trust 2000368/Z/15/ZWellcome Trust 200368/Z/15/Z
6 · The paper itself

Abstract

The Finnish population is a unique example of a genetic isolate affected by a recent founder event. Previous studies have suggested that the ancestors of Finnic-speaking Finns and Estonians reached the circum-Baltic region by the 1

Indexed as

AllelesGenome, HumanPedigreeDNA, AncientEstoniaFemaleFinlandGenealogy and HeraldryGene FrequencyHigh-Throughput Nucleotide SequencingHistory, 21st CenturyHistory, AncientHistory, MedievalHuman MigrationHumansLanguageDNA, Ancientancient DNAcommunity structureEstonian BiobankFinnish bottleneckidentity by descentimputationlong shared allele intervalsmedieval Estonian genomespopulation structure

Identifiers

PMID34411538
PMCPMC8456179

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.