Evidence map›Paper›PMID 34411371›Full record

ArticleCytopathology : official journal of the British Society for Clinical Cytology2022

Diagnostic impact of safety protocols for processing peritoneal washing specimens during the global pandemic of coronavirus disease 2019: A comparative study from 195 cytological samples.

Angela Santoro, Giuseppe Angelico, Maria Gaia Mastrosimini, Frediano Inzani, Federica Cianfrini, Patrizia Straccia, Damiano Arciuolo, Nicoletta D'Alessandris, Giulia Scaglione, Saveria Spadola and 2 more

Abstract readComparative Study
In one paragraph

Article in Cytopathology : official journal of the British Society for Clinical Cytology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Angela SantoroDipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Unità Operativa Complessa di Gineco-patologia e Patologia Mammaria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Giuseppe AngelicoDipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Unità Operativa Complessa di Gineco-patologia e Patologia Mammaria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Maria Gaia MastrosiminiDepartment of Diagnostics and Public Health, G.B. Rossi University Hospital, Verona, Italy.
Frediano InzaniDipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Unità Operativa Complessa di Gineco-patologia e Patologia Mammaria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Federica CianfriniDipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Unità Operativa Complessa di Gineco-patologia e Patologia Mammaria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Patrizia StracciaDivision of Anatomic Pathology and Histology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID 0000-0003-3256-8293
Damiano ArciuoloDivision of Anatomic Pathology and Histology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Nicoletta D'AlessandrisDipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Unità Operativa Complessa di Gineco-patologia e Patologia Mammaria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Giulia ScaglioneDipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Unità Operativa Complessa di Gineco-patologia e Patologia Mammaria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Saveria SpadolaDipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Unità Operativa Complessa di Gineco-patologia e Patologia Mammaria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Esther Diana RossiDivision of Anatomic Pathology and Histology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID 0000-0003-3819-4229
Gian Franco ZannoniDipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Unità Operativa Complessa di Gineco-patologia e Patologia Mammaria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-4473-7560

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe global pandemic of the coronavirus disease 2019 represents a major concern for health services worldwide, and has also induced major changes in cytopathology practice.

aimWe aimed to verify the diagnostic performance of cytological evaluation under a new safety protocol during the pandemic compared to the standard pre-pandemic procedure. We also aimed to assess how cytological diagnoses and sampling were impacted during the pandemic period compared to the pandemic-free period in 2019. MATERIALS AND

methodsCytological samples of peritoneal washings taken during the first 10 months of the pandemic emergency in Italy (March 11, 2020 to January 11, 2021) were compared to samples from the preceding 10-month time frame (May 11, 2019 to March 10, 2020).

resultsOne hundred ninety-five specimens were analysed in the present study. We observed no noticeable differences in cytological diagnoses during the pandemic period compared to the pre-pandemic period. The case numbers by diagnostic category for the pre-pandemic vs pandemic periods, respectively, were as follows: non-diagnostic, 0 vs 0 cases; negative for malignancy, 86 vs 52 cases; atypia of uncertain significance, 7 vs 1 cases; suspicious for malignancy, 0 vs 2 cases; malignant, 42 vs 4 cases.

conclusionWhile a consistent reduction in the number of cytological examinations has been observed during the COVID-19 period, our institutional safety protocol for processing cytological samples did not affect the diagnostic reliability of peritoneal washing cytology.

Indexed as

CytodiagnosisCytological TechniquesCOVID-19HumansItalyNeoplasmsSARS-CoV-2Specimen HandlingCOVID-19cytopathologyInternational System for Reporting Serous Fluid Cytology (TIS)liquid-based cytologymalignancy rateperitoneal washings

Identifiers

PMID34411371
PMCPMC8420544

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.