Evidence map›Paper›PMID 34411246›Full record

Observational studyPain medicine (Malden, Mass.)2021

First-Year Trajectories of Medical Cannabis Use Among Adults Taking Opioids for Chronic Pain: An Observational Cohort Study.

Jonathan Ross, Deepika E Slawek, Chenshu Zhang, Joanna L Starrels, Frances R Levin, Nancy L Sohler, Haruka Minami, Julia H Arnsten, Chinazo O Cunningham

Open access · bronzeAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Pain medicine (Malden, Mass.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jonathan RossDivision of General Internal Medicine, Department of Medicine, Montefiore Health System, Bronx, New York, USA.ORCID 0000-0001-6126-3048
Deepika E SlawekDivision of General Internal Medicine, Department of Medicine, Montefiore Health System, Bronx, New York, USA.
Chenshu ZhangDivision of General Internal Medicine, Department of Medicine, Montefiore Health System, Bronx, New York, USA.
Joanna L StarrelsDivision of General Internal Medicine, Department of Medicine, Montefiore Health System, Bronx, New York, USA.
Frances R LevinDivision on Substance Use Disorders, NY State Psychiatric Institute, New York, New York, USA.
Nancy L SohlerDepartment of Community Health and Social Medicine, City University of New York, New York, New York, USA.
Haruka MinamiDepartment of Psychology, Fordham University, Bronx, New York, USA.
Julia H ArnstenDivision of General Internal Medicine, Department of Medicine, Montefiore Health System, Bronx, New York, USA.
Chinazo O CunninghamDivision of General Internal Medicine, Department of Medicine, Montefiore Health System, Bronx, New York, USA.
Montefiore Health System · USCity University of New York · USColumbia University Irving Medical Center · USFordham University · US

Funding

Patient and Population Health Outcomes Research SWGP30AI124414 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Vilma Gabbay · 2017 to 2026
$28.3M
Integrated Care for Chronic Pain and Opioid Use Disorder: The IMPOWR Research Center at Montefiore/Einstein (IMPOWR-ME)RM1DA055437 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI ARNSTEN, JULIA H., GABBAY, VILMA · 2021 to 2025
$13.7M
Does medical cannabis reduce opioid analgesics in HIV+ and HIV- adults with pain?R01DA044171 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ARNSTEN, JULIA H. · 2017 to 2021
$3.8M
The Neural Underpinnings of Depression and Cannabis Use in Young PLWHR01DA054885 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Vilma Gabbay, Anjali Sharma · 2021 to 2026
$3.2M
Minimizing losses from HIV care under universal treatment in RwandaK23MH114752 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ROSS, JONATHAN · 2017 to 2021
$995k
Mentoring researchers on drug abuse and HIVK24DA036955 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CUNNINGHAM, CHINAZO · 2014 to 2019
$911k
Mentoring Junior Investigators to Tackle the Opioid EpidemicK24DA046309 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STARRELS, JOANNA L. · 2018 to 2023
$876k
Acute Effects of Cannabis on Cognition and Mobility in Older HIV-Infected and Uninfected Women"R21AG059505 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SHARMA, ANJALI · 2018 to 2019
$318k
Einstein-Rockefeller-CUNY Center for AIDS Research P30-AI124414Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentFIC NIH HHSNational Institute of Allergy and Infectious DiseasesNCI NIH HHSNHLBI NIH HHSNIAID NIH HHS P30 AI124414NIA NIH HHS R21 AG059505NIDA NIH HHS K24 DA036955NIDA NIH HHS K24 DA046309NIDA NIH HHS R01 DA044171NIDA NIH HHS R01DA044171NIDA NIH HHS R01 DA054885NIDA NIH HHS RM1 DA055437NIH HHSNIMH NIH HHS K23 MH114752Office of AIDS Research
6 · The paper itself

Abstract

objectiveTo describe first-year trajectories of medical cannabis use and identify characteristics associated with patterns of use in a cohort of adults using opioids for chronic pain.

designLatent class trajectory analysis of a prospective cohort study using data on the 14-day frequency of medical cannabis use.

settingA large academic medical center and four medical cannabis dispensaries in the New York City metropolitan area. SUBJECTS: Adults with chronic pain using opioids and newly certified for medical cannabis in New York between 2018 and 2020.

methodsUsing latent class trajectory analysis, we identified clusters of participants based on the 14-day frequency of medical cannabis use. We used logistic regression to determine factors associated with cluster membership, including sociodemographic characteristics, pain, substance use, and mental health symptoms.

resultsAmong 99 participants, the mean age was 53 years; 62% were women, and 52% were White. We identified three clusters of medical cannabis use: infrequent use (n = 30, mean use = 1.5 days/14-day period), occasional use (n = 28, mean = 5.7 days/14-day period), and frequent use (n = 41, mean = 12.1 days/14-day period). Within clusters, use patterns did not vary significantly over 52 weeks. Differences were observed in two sociodemographic variables: Frequent (vs infrequent) use was associated with non-Hispanic White race/ethnicity (adjusted odds ratio 4.54, 95% confidence interval 1.49-14.29), while occasional (vs infrequent) use was associated with employment (adjusted odds ratio 13.84, 95% confidence interval 1.21-158.74).

conclusionsThree clusters of medical cannabis use patterns emerged and were stable over time. Results suggest that structural factors related to race/ethnicity and employment may be major drivers of medical cannabis use, even among adults certified for its use.

Indexed as

CannabisChronic PainMedical MarijuanaAdultAnalgesics, OpioidFemaleHumansMaleMiddle AgedNew York CityProspective StudiesAnalgesics, OpioidMedical MarijuanaCannabisChronic PainComplementary MedicineMedical CannabisPain Management

Identifiers

PMID34411246
PMCPMC8665992
OpenAlexW3194871388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.