Evidence map›Paper›PMID 34411100›Full record

ArticlePLoS computational biology2021

Ten simple rules for creating reusable pathway models for computational analysis and visualization.

Kristina Hanspers, Martina Kutmon, Susan L Coort, Daniela Digles, Lauren J Dupuis, Friederike Ehrhart, Finterly Hu, Elisson N Lopes, Marvin Martens, Nhung Pham and 7 more

Abstract readEditorial
In one paragraph

Article in PLoS computational biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Pathway Analysis Interpretation in the Multi-Omic Era.Biotech (Basel (Switzerland)) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Exploration and comparison of molecular mechanisms across diseases using MINERVA Net.Protein science : a publication of the Protein Society · 2023
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Kristina HanspersInstitute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, California, United States of America.ORCID 0000-0001-5410-599X
Martina KutmonDepartment of Bioinformatics-BiGCaT, NUTRIM, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0002-7699-8191
Susan L CoortDepartment of Bioinformatics-BiGCaT, NUTRIM, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0003-1224-9690
Daniela DiglesDepartment of Pharmaceutical Sciences, Division of Pharmaceutical Sciences, University of Vienna, Vienna, Austria.ORCID 0000-0001-5934-3559
Lauren J DupuisDepartment of Bioinformatics-BiGCaT, NUTRIM, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0003-2606-3045
Friederike EhrhartDepartment of Bioinformatics-BiGCaT, NUTRIM, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0002-7770-620X
Finterly HuDepartment of Bioinformatics-BiGCaT, NUTRIM, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0002-8416-4533
Elisson N LopesInstituto de Ciencias Biologicas, Departamento de Bioquimica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0003-1661-6304
Marvin MartensDepartment of Bioinformatics-BiGCaT, NUTRIM, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0003-2230-0840
Nhung PhamDepartment of Bioinformatics-BiGCaT, NUTRIM, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0003-3091-3962
Woosub ShinDepartment of Bioinformatics-BiGCaT, NUTRIM, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0002-2319-2960
Denise N SlenterDepartment of Bioinformatics-BiGCaT, NUTRIM, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0001-8449-1318
Andra WaagmeesterMicelio, Antwerp, Belgium.ORCID 0000-0001-9773-4008
Egon L WillighagenDepartment of Bioinformatics-BiGCaT, NUTRIM, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0001-7542-0286
Laurent A WinckersDepartment of Bioinformatics-BiGCaT, NUTRIM, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0002-9454-4783
Chris T EveloDepartment of Bioinformatics-BiGCaT, NUTRIM, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0002-5301-3142
Alexander R PicoInstitute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, California, United States of America.ORCID 0000-0001-5706-2163

Funding

The Gene Wiki: Community intelligence applied to gene annotationR01GM089820 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI SU, ANDREW I · 2010 to 2021
$5.2M
WikiPathways Project: At the Intersection of Big Data and Researcher KnowledgeR01GM100039 · NIGMS · J. DAVID GLADSTONE INSTITUTES · PI PICO, ALEXANDER R · 2012 to 2020
$3.4M
NIGMS NIH HHS R01 GM089820NIGMS NIH HHS R01 GM100039
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Metabolic Networks and PathwaysModels, BiologicalAnimalsComputational BiologyComputer GraphicsDatabases, FactualHumansTerminology as Topic

Identifiers

PMID34411100
PMCPMC8375987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.