Evidence map›Paper›PMID 34410981›Full record

ArticleIn vivo (Athens, Greece)

Ten Daily Fractions for Whole Breast Cancer Irradiation: Long Term Results.

Liliana Belgioia, Alessandra Fozza, Luca Trapani, Luca Carmisciano, Francesca Cavagnetto, Stefano Agostinelli, Marina Guenzi, Daniele Friedman, Piero Fregatti, Renzo Corvò

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liliana BelgioiaDepartment of Health Science (DISSAL), University of Genoa, Genoa, Italy; liliana.belgioia@unige.it.
Alessandra FozzaRadiation Oncology Department, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Luca TrapaniDepartment of Health Science (DISSAL), University of Genoa, Genoa, Italy.
Luca CarmiscianoDepartment of Health Science (DISSAL), Biostatistics Unit, University of Genoa, Genoa, Italy.
Francesca CavagnettoMedical Physics Department, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Stefano AgostinelliMedical Physics Department, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Marina GuenziRadiation Oncology Department, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Daniele FriedmanDepartment of Surgical Science and Integrated Diagnostic (DISC), University of Genoa, Genoa, Italy.
Piero FregattiDepartment of Surgical Science and Integrated Diagnostic (DISC), University of Genoa, Genoa, Italy.
Renzo CorvòDepartment of Health Science (DISSAL), University of Genoa, Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimTo report the feasibility and oncological outcomes in breast cancer patients treated with a short hypofractionated radiotherapy schedule. PATIENTS AND

methodsWe evaluated 380 breast cancer patients treated with ten daily fractions of radiotherapy up to 39 Gy on tumor bed. Primary endpoint was local relapse rate (LRR). Secondary endpoints were overall survival (OS) and metastasis-free survival (MFS).

resultsThe median follow up was 5.0 years. Two- and 5-year LRR rates were 0.2 and 2%, respectively. Two- and 5-year MFS rates were 96.1% and 90.5%, respectively. Two and 5-year OS rates were 97.4% and 95%, respectively.

conclusionThis short schedule may represent an alternative option to standard mild hypofractionated radiotherapy in breast cancer patients due to its excellent feasibility and very low recurrence rate.

Indexed as

Breast NeoplasmsMastectomy, SegmentalDose Fractionation, RadiationFemaleFollow-Up StudiesHumansNeoplasm Recurrence, LocalRadiotherapy, Adjuvantadjuvant treatmentearly breast cancerHypofractionated radiotherapylocal relapsetoxicity

Identifiers

PMID34410981
PMCPMC8408691

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.