Evidence map›Paper›PMID 34410958›Full record

ArticleIn vivo (Athens, Greece)

The Contribution of a Collagen Patch Coated With Fibrin Glue in Sealing Upper Gastrointestinal Defects: An Experimental Study.

Gregory Christodoulidis, Athina A Samara, Theodoros Floros, Kostas-Sotirios Karakantas, Prokopis-Andreas Zotos, Antonios Koutras, Konstantinos Tepetes

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gregory ChristodoulidisLaboratory of Experimental Surgery, University of Thessaly, Larissa, Greece.
Athina A SamaraLaboratory of Experimental Surgery, University of Thessaly, Larissa, Greece; at.samara93@gmail.com.
Theodoros FlorosLaboratory of Experimental Surgery, University of Thessaly, Larissa, Greece.
Kostas-Sotirios KarakantasLaboratory of Experimental Surgery, University of Thessaly, Larissa, Greece.
Prokopis-Andreas ZotosLaboratory of Experimental Surgery, University of Thessaly, Larissa, Greece.
Antonios Koutras1 Department of Obstetrics and Gynecology, Alexandra Maternity Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Konstantinos TepetesLaboratory of Experimental Surgery, University of Thessaly, Larissa, Greece.
University of Thessaly · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimWe aimed to evaluate the safety and efficacy of sealing primary upper gastrointestinal (GI) perforations with a collagen patch coated with fibrin glue (Tachosil MATERIALS AND

methodsThirty New Zealand rabbits were used in this study. An iatrogenic gastric perforation was created, and primary repair was performed on the control group. Tachosil

resultsLeakage was observed in 3 (20%) and 2 rabbits (13.3%) in the control and intervention group, respectively; however, the difference was not statistically significant (p=0.62). Moreover, adhesions formed in 10/15 and all rabbits in the intervention and control group, respectively (p=0.014); however, based on the Zuhlke adhesion's classification, there was no statistically significant difference between the two groups.

conclusionA collagen patch coated with fibrin glue is not a replacement but can be considered a safe option for the reinforcement of suturing, preventing leakages in the upper GI tract.

Indexed as

Fibrin Tissue AdhesiveUpper Gastrointestinal TractAnimalsCollagenRabbitsTissue AdhesionsCollagenFibrin Tissue Adhesivefibrin glueleakagesperforationTachosil®Upper GI

Identifiers

PMID34410958
PMCPMC8408736
OpenAlexW3193762777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.