Evidence map›Paper›PMID 34410849›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2021

Inflammation and metabolism gene sets in subcutaneous abdominal adipose tissue are altered 1 hour after exercise in adults with obesity.

A C Ludzki, M W Schleh, E M Krueger, N M Taylor, B J Ryan, T C Baldwin, J B Gillen, C Ahn, P Varshney, J F Horowitz

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

A C LudzkiSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan.
M W SchlehSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan.
E M KruegerSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan.
N M TaylorSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan.
B J RyanSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0001-5848-6988
T C BaldwinSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan.
J B GillenSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0001-7974-5395
C AhnSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan.
P VarshneySchool of Kinesiology, University of Michigan, Ann Arbor, Michigan.
J F HorowitzSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-3851-777X
University of Michigan · USUniversity of Toronto · CA

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Kanakadurga Singer · 2010 to 2026
$20.3M
TRAINING PROGRAM IN ENDOCRINOLOGY AND METABOLISM.T32DK007245 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RICHARD J. AUCHUS · 1986 to 2026
$7.2M
Insulin sensitivity and fatty acid partitioning in skeletal muscle after exerciseR01DK077966 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOROWITZ, JEFFREY F · 2010 to 2020
$4.9M
The role of iron in adipose tissue lipolysis, systemic fatty acid mobilization, and insulin resistance in obese humansF32DK117522 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RYAN, BENJAMIN · 2018 to 2020
$87k
NIDDK NIH HHS F32 DK117522NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK089503NIDDK NIH HHS R01 DK077966NIDDK NIH HHS T32 DK007245NIH HHS F32DK117522NIH HHS R01DK077966NIH HHS T32DK007245
6 · The paper itself

Abstract

Although the health benefits of exercise in adults with obesity are well described, the direct effects of exercise on adipose tissue that may lead to improved metabolic health are poorly understood. The primary aims of this study were to perform an unbiased analysis of the subcutaneous abdominal adipose tissue transcriptomic response to acute exercise in adults with obesity, and to compare the effects of moderate-intensity continuous exercise versus high-intensity interval exercise on this response. Twenty-nine adults with obesity performed a session of either high-intensity interval exercise (HI; 10 × 1 min at 90%HRpeak, 1 min recovery between intervals;

Indexed as

ExerciseObesityAbdominal FatAdipose TissueAdultFemaleHumansInflammationSubcutaneous Fatacute exerciseadipose tissueHIITobesitytranscriptomics

Identifiers

PMID34410849
PMCPMC8560390
OpenAlexW3193793871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.